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For example, a case definition that is too broad would include individuals with other illnesses and conditions, complicating the tasks of estimating prevalence rates or identifying effective treatment programs. A consensus on a research case definition and its operationalization and assessment would enable investigators to select more homogenous samples that could expedite the identification of valid biological markers, and consequently reduce misperceptions regarding the role of psychogenic versus biomedical factors. Our editorial reviews the implications of previous research and clinical case definitions in CFS and ME domains.
Source: Leonard A. Jason, Pamela A. Fox & Kristen D. Gleason. The importance of a research case definition. Fatigue: Biomedicine, Health & Behavior. Pages 1-7 | Received 01 Aug 2017, Accepted 04 Oct 2017, Published online: 12 Oct 2017