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The rise & fall of the Chronic Fatigue Syndrome (CFS) as defined by Holmes et al.

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Source: Medical Hypotheses 1996 Feb;46(2):63-6

This paper is a sequel to my monograph on neurocirculatory asthenia
and chronic fatigue syndrome. It pays special attention to the
nature of chronic fatigue syndrome, to the forms of
neurocirculatory asthenia, and above all to the 6th form in
which profound fatigue is the dominant symptom. All forms
including the 6th are characterized by the presence of
concomitant symptoms due to dysfunction of the autonomic
nervous system. Chronic fatigue syndrome as defined by Holmes
et al is devoid of these symptoms. Up till the present day no
case histories of it have been published. It is argued that
chronic fatigue syndrome sensu Holmes et al does not exist,
the 6th form of neurocirculatory asthenia having to take up
its place.

van Waveren EK

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