SAM-e (S-adenosylmethionine) is a compound produced by the body from methionine, a sulfur-containing amino acid, and ATP, an energy producing compound.
SAM-e has shown promise in treating the symptoms of fibromyalgia. Several studies have shown a reduction in the number of tender points and amount of pain, as well as improvement in mood, in people with fibromyalgia who took SAM-e [Am Jour Med 1987 Nov 20;83]. (Source: Natural Treatments for Fibromyalgia: An A to Z Guide, by Kenna Simmons. An official publication of the Arthritis Foundation. To purchase, visit www.arthritis.org.)