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Tube phagocytosis, a novel way for neutrophils to Phagocytize borrelia burgdorferi.

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Abstract

Interactions between human neutrophils and Borrelia burgdorferi, the
Lyme disease spirochete, were studied by dark-field microscopy combined with video technology. A previously unrecognized mechanism for neutrophils to phagocytize the spirochete was discovered. During phagocytosis, the spirochete attaches to the neutrophil head-on, the neutrophil forms a thin tubelike protrusion around the bacterium, and the fully covered spirochete is drawn into the cell.

Infect Immun. 1998 Jul;66(7):3433-5. Research Support, Non-U.S. Gov’t

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