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Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in people with chronic fatigue

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Editor’s Note: Ubiquinol-10 and COQ-10 may help to alleviate symptoms of chronic fatigue in people with Lyme disease. Ubiquinol-10 also supports heart health and may be useful for protecting the heart in Lyme disease. Some Lyme-literate health care practitioners recommend this supplement to their patients.
 
Abstract
 
The aim of this study was to evaluate the benefit of oral ubiquinol-10 supplementation in CFS patients using an open-label study and a randomized, double-blinded, placebo-controlled (RCT) study.
 
Twenty patients with CFS were randomly enrolled in an 8-week open-label oral ubiquinol-10 (150 mg ubiquinol-10/day) study. The patients and the attending physicians were not blinded to the supplementation. Forty-three patients with CFS were randomly assigned to receive either ubiquinol-10 (150 mg/day) or placebo every day for 12 weeks.
 
The patients and the attending physicians were blinded to the supplementation, and a total of 31 patients (N = 17 in the ubiquinol group and 14 in the placebo group) completed the study. The beneficial effects of ubiquinol-10 were observed in the open-label study we conducted prior to the RCT.
 
The RCT results suggest that supplementation with ubiquinol-10 for 12 weeks is effective for improving several CFS symptoms. © 2016 BioFactors, 42(4):431-440, 2016. © 2016 International Union of Biochemistry and Molecular Biology.
 
Source By Fukuda S. Nojima J4, Kajimoto O5, Yamaguti K3,6, Nakatomi Y3,6, Kuratsune H1,3,6, Watanabe Y2,3. Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome. Biofactors. 2016 Jul 8;42(4):431-40. doi: 10.1002/biof.1293. Epub 2016 Apr 29.
 

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