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Viral arthritis

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Viral infections can present with different patterns of joint and
soft tissue involvement, and the etiologic role of viruses in
various rheumatic diseases is a subject of continued great
interest. Recently, new immunoenzymatic assays have brought a
better understanding of the relationship between hepatitis C
virus serotypes and their immunologic manifestations. Our
knowledge of the consequences of parvovirus B19 infection has
broadened to include the variable clinical spectrum the role
of inflammatory cytokine production in parvovirus-induced
arthritis, a postulated causative role for B19 in rheumatoid
arthritis, and a negative association between parvovirus and
Still's disease as well as chronic fatigue syndrome. New,
specific antibodies to nonstructural protein NS-1 in
parvovirus B19-associated arthritis have been detected.
Arthritis related to hepatitis B virus vaccination or measles
and mumps vaccination was also reported. The papers reviewed
here demonstrate the continuing efforts in defining the
etiopathogenesis of virus-induced rheumatic diseases.

Schnitzer TJ, Penmetcha M

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