~Source: Life Extension, April 8, 2013.
April 8, 2013. The March, 2013 issue of The Journal of Clinical Endocrinology & Metabolism reports the finding of researchers at Newcastle University in England of a positive effect for vitamin D supplementation on the muscle function of deficient adults.
Dr, Akash Sinha and colleagues used magnetic resonance spectroscopy in a lower leg muscle of twelve participants before and after twelve weeks of vitamin D supplementation to evaluate phosphocreatine recovery kinetics as an assessment of mitochondrial oxidative phosphorylation. Phosphocreatine is used by the cells’ mitochondria to manufacture adenosine triphosphate (ATP)–a molecule needed by muscle for movement. Rapid replenishment of phosphocreatine by the mitochondria following muscle contraction is an indicator of improved mitochondrial efficiency.
The team observed a reduction in phosphocreatine recovery half-time after treatment with vitamin D, which indicates an improvement in maximal oxidative phosphorylation. “The scans provided a unique window into what is really going on in the muscle as it works,” Dr Sinha explained. “Examining this small group of patients with vitamin D deficiency who experienced symptoms of muscle fatigue, we found that those with very low vitamin D levels improved their muscle efficiency significantly when their vitamin D levels were improved.”
“We have proved for the first time a link between vitamin D and mitochondria function,” Dr Sinha announced. “Of the patients I see, around 60% are vitamin D deficient and most people living north of Manchester will struggle to process enough vitamin D from sunlight alone, particularly during winter and spring. So a simple vitamin D tablet could help boost your energy levels – from within the cells.”