Vitamin D insufficiency in southern Arizona – Source: American Journal of Clinical Nutrition, Mar 2008

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[Note: in this study, vitamin D concentration of < [less than] 20 ng/mL was considered deficient.]

Background: Vitamin D deficiency or insufficiency has been observed among populations in the northern United States. However, data on the prevalence of vitamin D deficiency in areas of high sun exposure, such as Arizona, are limited.

Objective: The purpose of this study was to analyze serum 25-hydroxyvitamin D [25(OH)D] concentrations in residents of southern Arizona and to evaluate predictors of 25(OH)D in this population.

Design: Cross-sectional analyses of serum from participants in a colorectal adenoma prevention study were conducted to determine rates of vitamin D deficiency.

Participants were categorized into 4 groups on the basis of serum 25(OH)D concentrations: <10.0 ng/mL, > or =10.0 ng/mL and <20.0 ng/mL, > or =20.0 ng/mL and <30.0 ng/mL, and > or =30.0 ng/mL.

Results: The mean serum 25(OH)D concentration for the total population was 26.1 +/- 9.1 ng/mL.

Of 637 participants:

• 22.3% had 25(OH)D concentrations [greater than] >30 ng/mL,

• 25.4% had concentrations [less than] <20 ng/mL,

• And 2.0% had concentrations <10 ng/mL.

Blacks (55.5%) and Hispanics (37.6%) were more likely to have deficient 25(OH)D concentrations (<20 ng/mL) than were non-Hispanic whites (22.7%).

Sun exposure had a greater effect on 25(OH)D in whites than in blacks and Hispanics, whereas BMI appeared to be more important in the latter groups.

Conclusion: Despite residing in a region with high chronic sun exposure, adults in southern Arizona are commonly deficient in vitamin D deficiency, particularly blacks and Hispanics.

Source: American Journal of Clinical Nutrition, Mar 2008;87(3):608-13. PMID: 18326598, by Jacobs ET, Alberts DS, Foote JA, Green SB, Hollis BW, Yu Z, Martínez ME. Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA. [E-mail: jacobse@u.arizona.edu ]

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