Reprinted with the kind permission of Life Extension.
June 3 2016. A study reported on May 20, 2016 in Environmental and Molecular Mutagenesis describes a significant benefit for supplementation with 31 nutrients in a transgenic mouse model of accelerated aging.
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“The findings are dramatic,” stated lead author Jennifer A. Lemon, who is a research associate in the Department of Biology at McMaster University. “Our hope is that this supplement could offset some very serious illnesses and ultimately improve quality of life.”
Dr Lemon and her colleagues gave transgenic and normal mice a daily supplement that contained vitamins B1, B3, B6, B12, C, D and E; acetyl-L-carnitine, alpha-lipoic acid, aspirin, beta-carotene, bioflavonoids, chromium picolinate, cod liver oil, CoQ10, DHEA, flax seed oil, folic acid, garlic, ginger, Ginkgo biloba, ginseng, green tea, L-glutathione, magnesium, melatonin, N-acetylcysteine, potassium, rutin, selenium and zinc. Animals received the supplement from the time of weaning throughout their lifespan. Untreated transgenic and normal mice served as controls.
Transgenic mice treated with the supplement failed to undergo the loss of brain cells and cognitive decline experienced by older untreated transgenic animals. They also had a better sense of smell and vision accompanied by an increase in photoreceptor cells. “The extent of functional benefits attained by our multi-ingredient dietary supplement here and in earlier studies strongly suggests that aging animals retain the capacity to support youthful phenotypes and that powerful impacts can be achieved through multi-ingredient dietary supplementation that addresses the multifactorial nature of aging organisms,” the authors conclude.
“The research suggests that there is tremendous potential with this supplement to help people who are suffering from some catastrophic neurological diseases,” Dr Lemon commented. “We know this because mice experience the same basic cell mechanisms that contribute to neurodegeneration that humans do. All species, in fact. There is a commonality among us all.”