Get FREE U.S. Shipping on $75 Orders*

Meperidine induced seizure in a patient with lyme borreliosis.

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)


A 15 years old child with
Lyme borreliosis was treated with meperidine via a patient controlled analgesia (PCA) pump for pain management. He had no history of seizure and had normal hepatic and renal functions. At the 7th hour of meperidine PCA delivery, generalized tonic-clonic seizure was developed and successfully suppressed with antiepileptics and no neurologic sequel was occurred. The total meperidine consumption in the patient was quite lower than the recommended doses with PCA. Although
Lyme disease might also cause seizure activities, the timing of the seizures was related with the accumulation of normeperidine which is the main metabolite of meperidine with central nervous system stimulant effect. The meperidine pain management on patients with
Lyme syndrome should be reconsidered to avoid undesired effects.Keywords.

J Clin Med Res. 2009 Dec;1(5):302-4. doi: 10.4021/jocmr2009.12.1277. Epub 2009 Dec 28.

share this article

share your comments

Enrich and inform our Community. Your opinion matters!

Leave a Reply

Your email address will not be published. Required fields are marked *

ProHealth CBD Store