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Oral Management of Pediatric Lyme Meningitis

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Guidelines for pediatric Lyme meningitis recommend treatment with parenteral therapy [1, 2]. Adult studies suggest that Lyme meningitis can be successfully treated with oral therapy. Our objective was to evaluate the clinical response, side effects and outcome of oral therapy for Lyme meningitis in the pediatric population compared with parenteral therapy in an area endemic for Lyme disease.


We conducted a case series chart review from January 2012 to May 2017 of pediatrics patient diagnosed and treated for Lymemeningitis. We recorded clinical presentation, laboratory values, antimicrobial therapy and follow up after therapy to compare the efficacy of oral versus parenteral route of therapy.


We identified 38 patients diagnosed with Lyme meningitis. Thirty-two patients were discharge with exclusively oral therapy with: doxycycline and amoxicillin. We had only 2 patients developed potential adverse effects from oral doxycycline therapy. All patients treated with oral antibiotics had resolution of symptoms on follow up appointments.


Oral therapy for Lyme meningitis yields no serious adverse events, was well tolerated and showed resolution of symptoms

Source: By Lopez SMC1, Campfield BT1,2, Nowalk AJ1. Oral Management for Pediatric Lyme Meningitis. J Pediatric Infect Dis Soc. 2018 Aug 28. doi: 10.1093/jpids/piy072. [Epub ahead of print]

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By CStrasheim

Connie Strasheim is the author of multiple wellness books, including three on Lyme disease. She is also a medical copywriter, editor and healing prayer minister. Her passion is to help people with complex chronic illnesses find freedom from disease and soul-spirit sickness using whole body medicine and prayer, and she collaborates with some of the world’s best integrative doctors to do this. In addition to Lyme disease, Connie’s books focus on cancer, nutrition, detoxification and spiritual healing. You can learn more about her work at: ConnieStrasheim.com.

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