SAMe 200 - 200 mg, 60 enteric coated tablets by Doctor's Best

SAMe 200 has a rating of 3.0 stars based on 2 reviews.

Enhances Mood and Promotes Cognitive Health*

  • Essential for the healthy metabolism*
  • Promotes joint comfort and mobility*
  • Supports liver health and detoxification*
Usually: $21.99

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Doctor's Best SAMe is proven to enhance mood and promote cognitive health.

It is essential for the healthy metabolism of the major brain transmitters’ dopamine, serotonin and norepinephrine. In addition, SAMe promotes joint comfort and mobility and supports liver health and detoxification. SAMe effectiveness has been published in 18 controlled human trials published over 40 years. Doctor’s Best SAMe uses pharmaceutical grade materials. SAMe is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. SAMe optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed). Effectiveness of SAMe has been backed by at least 18 controlled human trials published over almost four decades.*

How does it work? S-Adenosyl Methionine (SAMe) is produced by the body from ATP and the amino acid methionine which is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.*

Why should I take Doctor's Best SAMe? SAM-e is a biological compound found in every living cell of the human body, vital to their function, stability and activity and involved in more than one hundred biochemical reactions and specific processes. SAMe helps promote healthy mood. So if your body is not producing enough SAMe, you might feel blue or have trouble sleeping.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results may vary.

Label Information

Supplement Facts
Serving Size: 1 tablet
Servings Per Container: 60
Amount Per Serving%DV
S-Adenosyl Methionine (from 400 mg of SAM-e tosylate disulfate)200 mg
† Daily Value not established.
  • Suggested Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.
  • Storage: Store in a cool, dry place. Keep out of reach of children.
  • Contraindications: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.
  • Other Ingredients: Cellulose, methacrylic acid copolymer, Glyceryl Behenate, Magnesium Silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide.
  • Contains No: yeast, dairy, gluten, soy, wheat, or artificial flavoring.

Frequently Asked Questions

What is the amount of active SS form in SAMe? The amount of active SS form is no less than 65%. What is the country of origin for Doctor's Best products? Doctor’s Best products are quality tested and manufactured in the United States using highly qualified cGMP manufacturers and raw material ingredients. Doctor’s Best sources raw materials from around the world and ingredients are subject to the intense testing and verification regardless of geography of origin.