Amino Sleep by ProHealth is a groundbreaking nutritional complex that features some of the most widely known sleep-supportive amino acids: Glycine, L-Tryptophan, 5-HTP, and L-Theanine.
Considered the building blocks of life, amino acids play many different health-promoting roles in the body, including helping with the formation of neurotransmitters. These chemical signaling compounds enable nerve-to-nerve communication throughout the brain and nervous system, and are needed to support healthy sleep patterns.
Some neurotransmitters send signals to the brain that help to keep us awake and alert; others regulate the body's relaxation and mood responses, helping to instill calm, peaceful feelings of drowsiness; and others send the brain signals to fall asleep and stay asleep. Emerging evidence suggests that by targeting these neurotransmitter pathways with amino acid nutrition, we may normalize sleep patterns and promote high-quality sleep that refreshes mind and body.
Let's take a closer look at how these amino acids, presented in ProHealth’s Amino Sleep, may combine to support rejuvenating rest in a new and different way.
Glycine - Helps You Wake Up Clear-Headed & Energized
Glycine is an amino acid that the body produces naturally. In the nervous system, glycine acts as an inhibitory neurotransmitter; this means when it reaches neurons, it calms them so they don't "fire" with as much electrical activity.2 Glycine is also believed to lower core body temperature and to relax blood vessels at night; both these biological activities have been tied to sleep onset and sleep quality.3
L-Tryptophan - Accelerates Sleep Onset; Extends Deep Delta-Wave Sleep
Stress and moodiness can wreak havoc on your sleep patterns. The amino acid L-Tryptophan may be perfectly suited to help with these concerns because it promotes a bright mood, relaxed mindset, and restful sleep patterns, all at the same time. L-Tryptophan has been suggested to be important in sleep management because, unlike some synthetic sleep aids, it is not associated with feelings of grogginess and brain fog upon waking.6
Did you know?
L-Tryptophan may be especially helpful for women, because research has shown women with low L-Tryptophan levels appear to be more susceptible to mood concerns and relaxation difficulties that can make sleep challenging.7
A portion of the body's circulating L-Tryptophan is delivered to the central nervous system (CNS), including the brain, where it is used to form neurotransmitters linked to relaxation and mood balance, including serotonin. In the brain, serotonin enhances production of melatonin, an important hormone for supporting normal circadian rhythm and restful sleep. In helping these brain chemicals, L-Tryptophan appears to support sleep.
Griffonia Simplicifolia (98% 5-HTP) - Supports Mood and Relaxation
Griffonia Simplicfolia seeds supply 5-hydroxy L-Tryptophan (5-HTP), an amino acid metabolite that the body uses to make the relaxing neurotransmitter serotonin.
Serotonin is an important contributor to tranquility and sleep, but is known to decline naturally in the body with age.10 Griffonia's 5-HTP may help because it is considered to be easy-to-absorb and highly bioavailable, and is also one of the few nutrients that can cross the blood-brain barrier. Here, in the brain, 5-HTP directly influences serotonin and other neurotransmitters associated with mood, relaxation and sleep patterns.
L-Theanine - Supports Non-Sedating Relaxation Responses
Do you have an excitable personality and racing thoughts that make it hard to "turn off" your brain to fall asleep? L-Theanine in Amino Sleep may be perfect for you. L-Theanine is an amino acid found in green and black tea that may be partially responsible for these beverages’ calming and soothing effects. Like 5-HTP, L-Theanine is capable of crossing the blood barrier and directly influencing brain neurotransmitters, resulting in feelings of relaxation.
3. Kawai N, Sakai N, et al. The Sleep-Promoting and Hypothermic Effects of Glycine are Mediated by NMDA Receptors in the Suprachiasmatic Nucleus, Neuropsychopharmacology, 2015, 40, 6, 1405
6. Richard D, Dawes M, et al. L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. International Journal of Tryptophan Research 2009:2.
7. Bell C., Abrams J., Nutt D. Tryptophan depletion and its implications for psychiatry. British Journal of Psychiatry 2001;178:399-405.
10. Payton A, et al. Influence of serotonin transporter gene polymorphisms on cognitive decline and cognitive abilities in a nondemented elderly population. Molecular Psychiatry (2005) 10, 1133–1139. doi:10.1038/sj.mp.4001733; published online 16 August 2005
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.