Found in broccoli and other cruciferous vegetables like cabbage, kale, and Brussels sprouts, sulforaphane is a powerful compound known as an isothiocyanate. Sulforaphane supports health by acting as a potent antioxidant, participating in detoxification, and improving cognitive and cardiovascular health.
Sulforaphane’s anti-aging and health-promoting properties are mediated through several processes, including reducing levels of oxidative stress — the accumulation of inflammatory compounds called reactive oxygen species (ROS) that damage our cells — and fighting body-wide inflammation.
As Dr. David Sinclair, the co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School and a professor in the Department of Genetics, states of the impressive compound, "Sulforaphane is very beneficial to boost the body's defense against DNA damage, which we know drives epigenetic changes."
However, despite this great potential, supplemental sulforaphane tends to have limited clinical use because of its poor stability and bioavailability in the body. One way to circumvent this issue is by using liposomal forms of sulforaphane. These nano-sized, bubble-shaped molecules have a unique structure that significantly boosts absorption and utilization in the body. With these tiny liposomes, we can get all of the benefits of sulforaphane — without ever having to eat one piece of broccoli.
Studies have demonstrated Sulforaphane's ability to support immune function and heart health. It has also been studied to support neurological health in children and metabolic function in adults. Many isothiocyanates, particularly sulforaphane, have been shown to promote the expression of antioxidant enzymes via the activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) dependent pathway.
Sulforaphane has demonstrated the ability to reduce the nuclear translocation of the pro-inflammatory transcription factor nuclear factor (NF)-Κb, which largely controls the production of other inflammatory cytokines such as TNF, IL-1 and IL-6.