Folic acid and folate are both forms of vitamin B9; folate is the naturally occurring form and folic acid is a synthetic version. However, neither are biologically active and both must go through a multi-step, sometimes inefficient, process to be converted to L-methylfolate before they can be used by the body.
The problem is that not everyone is able to complete that process. Studies have shown that a significant percentage of the population has a genetic enzyme deficiency known as the MTHFR mutation, which prevents the final step of the conversion process from occurring. For these individuals, folic acid supplements have little value and potentially may even be harmful.
On the other hand, Magnafolate® is biologically active so, unlike folic acid and folate, it does not have to be converted in order to be utilized by the body. This is especially good news for those who have the MTHFR mutation.
Magnafolate® is a patented, crystallized form of L-5-Methyltetrahydrofolate Calcium Salt that can cross the blood-brain barrier, does not mask Vitamin B12 deficiency, and is naturally utilized by the human body. When compared to other L-methylfolate products, Magnafolate® was found to have greater stability (at least three years), uniform particle size distribution, better dissolution, higher potency, and superior bioavailability.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.