SAM-e (S-adenosylmethionine) is a hard working molecule naturally produced in all living cells, it plays a key role in the biological process called methylation.

  • Promotes formation of healthy cells and connective tissue, for healthy joints,
  • Helps with the synthesis of enzymes & detoxifying glutathione in the liver, for healthy liver function,
  • Plays a role in synthesis of various hormones & neurotransmitters, including serotonin, melatonin, and adrenaline,
  • And regulates the expression of genes, apparently helping to suppress errors in DNA replication.

ProSAMe™ delivers the natural benefits of SAM-e via enteric coated tablets to the small intestine, where it can be absorbed into the bloodstream.

SAM-e and Healthy Joints

ProSAMe™ helps support cartilage-producing cells, keeping joints protected. It also promotes the cartilage molecules that retain water in the cells for enhanced joint flexibility & less pain. With ProSAMe™, you can be more active, whether it’s gardening or jogging you’ve been missing out on.

SAM-e and Healthy Liver Function

The compound structure of ProSAMe™ is actually one of the liver’s own essential nutrients. ProSAMe™ supplementation produces glutathione for detoxification, while replenishing the liver’s own SAMe.

Read more about ProSAMe™ in “SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood “

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Label Information

Supplement Facts
Serving Size: 1 tablet
Servings Per Container: 30
Amount Per Serving%DV
S-Adenosyl Methionine (from 800mg of SAMe tosylate dusulfate)400mg*
* Daily Value not established

Note: Do not use if outer seal blister pack is broken. This product complies with the proposed USP Monograph for SAMe.

  • Suggested Use:

    As a dietary supplement, take 1 to 2 tablets daily on an empty stomach, or as advised by your health care practitioner.

  • Storage: Store in a cool dry place. Keep out of reach of children.
  • Contraindications: Individuals using prescribed medications such as antidepressants, including Serotonin Re-uptake Inhibitors and MAO inhibitors should consult a physician before using. Individuals with Parkinson's disease, bipolar disorder or manic depression should not take ProSAMe™
  • Other Ingredients: Microcrystalline cellulose, mannitol, sodium starch glycolate, silicon dioxide, glycerol behenate, magnesium stearate (vegetable source), enteric coating (methacrylate copolymers), titanium dioxide, magnesium silicate, triethylcitrate, riboflavin, glycerol palmitostearate, and medium chain triglycerides. Contains salicylates.
  • Contains No: wheat, gluten, soy, dairy, egg, fish/shellfish, nuts/tree nuts. Suitable for vegetarians/vegans.
  • Salicylates: Yes