L-5-MTHF, by Seeking Health, uses 1,000 mcg of pure non- racemic l-methylfolate in an easy-to-deliver lozenge. Bioactive folate supports production and maintenance of new cells and is needed to make DNA and RNA, the building blocks of cells. Folate helps maintain the normal metabolism of homocysteine, a potentially harmful amino acid metabolite.* Deficiencies of folate are common, as many individuals do not consume enough folate-rich foods. Cooking or processing readily destroys folate present in food. Folic acid, the form of folate commonly used in fortified foods and supplements, must be reduced during absorption to become metabolically useful.

However, some individuals do not effectively convert folic acid into its active form, thus are still at risk of deficiency.* In addition, unmetabolized folic acid that enters the bloodstream cannot be used by cells and has anti-folate effects that may be deleterious.* L-5-MTHF is easily absorbed and used by cells. It is the predominant folate in circulation and the only folate that can cross the blood-brain barrier.* L-5-MTHF is an active, methylated form of folate. It requires no additional metabolic steps to be used by the body, thus it is often the preferred choice for those with absorption or metabolic defects.*

Key Benefits and Actions of L-5-MTHF by Seeking Health:

  • Supports Methylation*
  • Supports Homocysteine Metabolism*
  • Supports Nervous System Function*

This item cannot be shipped internationally. We sincerely apologize for any inconvenience.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results may vary.

Label Information

Supplement Facts
Serving Size: 1 lozenge
Servings Per Container: 60
Amount Per Serving %DV
Folate (as Quatrefolic (6S)-5-methyltetrahydrofolate, glucosamine salt) 1,000 mcg 250%
Daily Value Based on a standard 2,000 calorie daily intake
  • Suggested Use: Take 1 lozenge daily or as directed by your healthcare professional. Lozenge may be broken into smaller pieces if lower dosage is desired.
  • Storage: Store in a cool, dry place (59-85F) away from direct sunlight. Keep out of reach of children.
  • Other Ingredients: Xylitol, ascorbyl palmitate, silica, and natural orange flavor.
  • Contains No: Gluten, dairy, egg, soy, fish, shellfish, nuts, corn, GMO, or prebiotics.

Frequently Asked Questions

What is the percent of purity of L-5-methylfolate in this product? Methylfolate, as Quatrefolic, is 99% pure 6S isomer. What are the natural flavors in this product? L-5-MTHF Lozenge contains natural cherry flavor derived from sour cherry. How much is usually taken? We recommend taking one (1) lozenge per day, or as directed by a healthcare provider. Lozenge may be broken into smaller pieces if lower dosage is desired. What is the best way to cut these lozenges in half? The best way to do this is to use a serrated knife. Place the lozenge on a counter or cutting board. Then, holding the knife at about a 30 degree angle, push the knife edge down on one edge of the lozenge. Next, carefully push the serrated knife down onto the lozenge. It should break in half. To cut the lozenge in quarters, repeat this procedure. Is this product suitable for Vegans and Vegetarians? This product is suitable for vegetarians and vegans. Does this product contain any grain or grain-derived ingredients? Yes. This product contains natural flavors, including maltodextrin, an ingredient derived from corn. Does this product contain GMO ingredients? No, this product does not contain GMOs. Is this product free of Magnesium Stearate? Yes. This product does not contain Magnesium Stearate. Is it OK to store the lozenges in a vitamin organizer? It is best not to put this product in a vitamin organizer as some of the ingredients are susceptible to moisture. The lozenges should remain in the bottle where they will be more protected from environmental influences. Where is this formula manufactured? This product is manufactured in the United States. This product was made in a GMP and ISO 9001:2008 registered facility.