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ProHealth > Store Home > Men's Health > Ultra Natural Prostate with ApresFlex® and Standardized Lignans
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Ultra Natural Prostate with ApresFlex® and Standardized Lignans - 60 softgels

#N0591 - Prostate Health Supplement
$28.50 $38.00 SRP
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Maintain Healthy Prostate Function with the Most Scientifically Substantiated Nutrients

  • Promotes prostate comfort*
  • Maintain healthy prostate structure*
  • Key nutrients to support a healthy prostate gland*
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Ultra Natural Prostate formula provides scientifically validated standardized botanical extracts that have been shown to promote healthy prostate function. No other prostate protection formula provides such a broad array of nutrients to support the multiple factors involved in maintaining a healthy prostate gland.

Ultra Natural Prostate formula contains the most scientifically substantiated nutrients to help protect the prostate gland and maintain its healthy function. The latest formulation of Ultra Natural Prostate contains the following key ingredients:

  • Standardized lignans from flax seed and Norway spruce knotwood convert to enterolactone in the intestine, which is then absorbed into the bloodstream.(1)

  • AprèsFlex®, an extract of boswellia, is a superior inhibitor of the enzyme 5-lipoxygenase or 5-LOX. AprèsFlex® absorbs into the blood 52% better than previously available forms of boswellia, for superior effectiveness.(2)

  • Nettle root extract (Urtica dioica). Testosterone converts to estrogen at higher rates as men age. Prostate cells are sensitive to estrogen’s growth stimulatory effects. Nettle helps support prostate cells against excess estrogen levels.(3-5)

  • DeepExtract™ USPlus® saw palmetto extract. A number of normal biological events in aging men affect prostate function and structure. Saw palmetto has been shown to interfere with DHT activity in the prostate, inhibit alpha-adrenergic receptor activity (to support normal urinary flow), and help control inflammatory actions in the prostate gland.(6-10) DeepExtract™ is a patented, state-of-the-art, ultra-high pressure CO2 extraction technology that ensures the most complete bioactive extract profile available that most closely reflects the composition of premium, mature saw palmetto berries. The result is a superior formula containing key ingredients in higher concentrations than many other extracts.(11)
  • Pumpkin seed supercritical CO2 oil extract. From select European pumpkins, it enhances the composition of free fatty acids and augments saw palmetto's benefits.(12-17)

  • Pygeum. Normal aging results in levels of certain prostaglandins increasing in the prostate gland. Pygeum africanum extract helps suppress prostaglandin E2, keeping the prostate gland placid and promoting prostate comfort.(18-23)

  • Beta-sitosterol is a biologically active constituent of pygeum.(24) A standardized pygeum extract plus beta-sitosterol from other plant sources is included in this formula to help maintain healthy prostate structure.(25-26)

  • Graminex® Flower Pollen Extract™. European pollen extract has been shown to relax smooth muscle tone of the urethra, counteract DHT, and help regulate inflammatory reactions.(27-29)

  • Boron. In addition to helping protect bones, this mineral has been shown to slow elevation of prostate-specific antigen (PSA) - seemingly a result of boron's positive effect on the presence of protein-degrading enzymes in the prostate gland.(30-32)

  • Lycopene. This carotenoid associated with the tomato's red color helps maintain healthy DNA gene function in prostate cells.(33-41)

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.


  1. J Med Food. 2008 Jun;11(2):207-14.
  2. Mol Cell Biochem. 2011 Aug;354(1-2):189-97.
  3. Phytomedicine. 2007 Aug;14(7-8):568-79.
  4. Planta Med. 2000 Feb;66(1):44-7.
  5. Andrologia. 2012 May;44 Suppl 1:396-409
  6. Curr Opin Urol. 2005 Jan;15(1):45-8.
  7. Am J Chin Med. 2004;32(3):331-8.
  8. Public Health Nutr. 2000 Dec;3(4A):459-72.
  9. Adv Ther. 2010 Aug;27(8):555-63
  10. Minerva Urol Nefrol. 2010 Dec;62(4):335-40
  11. US Plus Corp.Unpublished study.
  12. Urol Int. 2011;87(2):218-24.
  13. Nutr Res Pract. 2009 Winter;3(4):323-7.
  14. Urol Int. 2006;77(3):269-74.
  15. Forsch Komplementarmed Klass Naturheilkd. 2000 Aug;7(4):200-4.
  16. Journal of Food Engineering 95 (2009) 208–213
  17. Int Urol Nephrol. 1991;23(1):51-5.
  18. Curr Med Res Opin. 1998;14(3):127-39.
  19. Cochrane Database Syst Rev. 2002;(1):CD001044.
  20. Endocrine. 2007 Feb;31(1):72-81.
  21. Prostate. 2010 Jul 1;70(10):1044-53
  22. Urology. 1999 Sep;54(3):473-8.
  23. Wien Klin Wochenschr. 1990 Nov 23;102(22):667-73.
  24. World J Urol. 2002 Apr;19(6):426-35.
  25. Biochem Biophys Res Commun. 2009 Feb 13;379(3):795-8
  26. Eur J Cancer Prev. 2006 Aug;15(4):353-61.
  27. Eur Urol. 2009 Sep;56(3):544-51.
  28. Nihon Hinyokika Gakkai Zasshi. 2002 May;93(4):539-47.
  29. BJU Int. 2000 May;85(7):836-41.
  30. Anticancer Agents Med Chem. 2010 May 1;10(4):346-51.
  31. Front Biosci (Schol Ed). 2011 Jan 1;3:205-15.
  32. Cancer Causes Control. 2007 Feb;18(1):71-7.
  33. BJU Int. 2003 Sep;92(4):375-8.
  34. Nutr Cancer. 2009 Nov;61(6):775-83.
  35. J Nutr. 2008 Jan;138(1):49-53.
  36. Aktuelle Urol. 2009 Jan;40(1):37-43.
  37. FASEB J. 2004 Jun;18(9):1019-21.
  38. J Natl Cancer Inst. 2002 Mar 6;94(5):391-8.
  39. Cancer Epidemiol Biomarkers Prev. 2004 Mar;13(3):340-5.
  40. Cancer Epidemiol Biomarkers Prev. 2004 Feb;13(2):260-9.
  41. J Med Food. 2006 Summer;9(2):284-6.

Supplement Facts
Serving Size: 2 softgels
Servings Per Container: 30
Amount Per Serving %DV
USPlus® Saw Palmetto CO2 DeepExtract™ (fruit) [std. to 85%-95% total fatty acids and sterols (272 mg)] 320 mg *
Graminex® Flower Pollen Extract™ (from Rye) 252 mg *
AprèsFlex® Indian frankincense (Boswellia serrata) extract (gum resin) [std. to 20% AKBA** (14 mg)] 70 mg *
Pumpkin seed oil extract [std to 85% total fatty acids (170 mg)] 200 mg *
Stinging and Dwarf nettle extracts (root) 240 mg *
Pygeum extract (bark) 100 mg *
Lycopene [from natural tomato extract (fruit)] 10 mg *
Phytosterol Complex [std. to 59% free total sterols (400 mg) and 26.6% free beta-sitosterol (180 mg)] 678 mg *
Proprietary Enterolactone Precursors Blend: HMRlignan™ Norway spruce (Picea abies) (knot wood) and Flax (seed) lignans extracts 20.15 mg *
Boron (from boron citrate, aspartate, glycinate) 3 mg *
* Daily value not established

AprèsFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas – Laila Nutra LLC. International patents pending. HMRlignan™ is a trademark used under sublicense from Linnea S.A. USPlus® and DeepExtract™ are trademarks of Valensa International and are used under license. US Patents 6,319,524 and 6,669,968.

** 3-O-acetyl-11-keto-ß-boswellic acid

Product & Usage Information:

  • Suggested Use: Take two softgels daily divided between morning and evening, with or without food, or as recommended by a healthcare practitioner.

  • Storage: KEEP OUT OF REACH OF CHILDREN. DO NOT EXCEED RECOMMENDED DOSE. Store in a cool, dry place. Close tightly after each use.

  • Other Ingredients: gelatin, glycerin, purified water, beeswax, sunflower lecithin, maltodextrin, rosemary extract. Contains soybeans.


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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.