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ProHealth > Store Home > Anti-Aging > Gamma E Tocopherol & Tocotrienols

Gamma E Tocopherol & Tocotrienols by Life Extension - 60 softgels

#N0832 - Tocopherol/Tocotrienol Supplement - By Life Extension
$31.50 $42.00 SRP
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$28.35
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A Powerful Antioxidant Compound*

  • Helps maintain cell membrane integrity and reduce cellular aging*
  • May enhance immune function*
  • Acts as a free radical scavenger*
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DESCRIPTION LABEL INFO ARTICLES REFERENCES
The term “vitamin E” refers to a family of eight related, lipid-soluble, antioxidant compounds widely present in plants. The tocopherol and tocotrienol subfamilies are each composed of alpha, beta, gamma, and delta fractions having unique biological effects. Different ratios of these compounds are found in different parts of a plant. For example, the green parts of a plant contain mostly alpha tocopherol and the seed germ and bran contain mostly tocotrienols. Along with other nutrients, tocopherols and tocotrienols are concentrated in the bran layers of the rye grain, and are only present at low levels in the flour endosperm. Tocopherols are also present in algae, mint teas, and other foods.102-105

One or more members of the vitamin E family may:

  • Maintain cell membrane integrity and reduce cellular aging107-109
  • Act as a free radical scavenger110-114
  • Maintain healthy platelet aggregation115-118
  • Promote a healthy nervous system and retina of the eye119-122
  • Maintain healthy cognitive function123-128
  • Enhance immune function129-133


According to a University of California study, alpha tocopherol (regular vitamin E) displaces critically important gamma tocopherol in the body. While alpha tocopherol inhibits free radical production, gamma tocopherol is required to trap and neutralize existing free radicals.134

Prestigious scientific journals have highlighted gamma tocopherol as one of the most critically important forms of vitamin E for those seeking optimal health benefits. In fact, studies show the combination of alpha and gamma-tocopherol supplementation appears to be superior to either supplementation alone on biomarkers of oxidative stress and on inflammatory factors.135,136

Most commercial vitamin E supplements contain little, if any, gamma tocopherol. They instead rely on alpha tocopherol as the primary ingredient. However, it is gamma tocopherol (not the alpha form) that quenches peroxynitrite, the free radical that plays a major role in the development of age-related decline.137

Tocotrienols have shown superior action in maintaining arterial health.143-146 In 2010, a team of Asian scientists demonstrated that this class of nutrients, which are difficult to obtain in sufficient quantities through dietary sources alone, may provide superior support in maintaining triglyceride levels already within healthy range in aging individuals. Just 120 mg per day of gamma-delta tocotrienols (provided in 3-4 softgels) induced a 28% decline in triglyceride levels in the blood after just one month.147 This wonder nutrient is so effective because of its structure of double bonds in the isoprenoid side chain, making it a great scavenger of free radicals.148

Research has shown that tocotrienols display potent neuroprotective properties and in particular alpha-tocotrienol is being touted as the most potent neuroprotective form of vitamin E.150-153

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.



*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

References

102. Proc Nutr Soc. 2003 Feb;62(1):117-22.
103. J Chromatogr A. 2004 Oct 29;1054(1-2):227-33.
104. Nahrung. 2004 Feb;48(1):34-7.
105. J Am Diet Assoc. 1979 Dec;75(6):647-65.
107. Clinics (Sao Paulo). 2012;67(2):135-43.
108.Oxid Med Cell Longev. 2012;2012:785743.
109. J Vasc Surg. 2004 Jan;39(1):229-37.
110.Diabetes Metab Res Rev. 2007 Oct;23(7):539-46
111. Antioxid Redox Signal. 2002 Oct;4(5):791-8.
112. Biol Chem. 2002 Mar-Apr;383(3-4):457-65.
113. Genes Nutr. 2012 Jan;7(1):91-8.
114. J Nutr. 2001 Feb;131(2):366S-368S.
115. J Nutr. 2001 Feb;131(2):374S-377S.
116. Circulation. 2007 Sep 25;116(13):1497-503.
117. Asia Pac J Clin Nutr. 2007;16(3):422-8.
118. Haematologica. 2002 Apr;87(4):420-6.
119. J Am Coll Nutr. 2004 Jun;23(3):233-8.
120. Fundam Clin Pharmacol. 2003 Dec;17(6):703-7.
121. J Neurosci Res. 2004 Mar 15;75(6):845-53.
122. Curr Eye Res. 2010 Sep;35(9):842-9.
123. Neurobiol Aging. 2002 Sep-Oct;23(5):737-45.
124.Alzheimers Dement. 2008 May;4(3):223-7.
125. J Nutr Health Aging. 2002;6(6):392-404.
126. Brain Res. 2001 Feb 16;892(1):211-7.
127.Iran Biomed J. 2008 Oct;12(4):217-22.
128. Toxicology. 2003 Jul 15;189(1-2):129-46.
129. Br J Cancer. 2003 Jun 16;88(12):1948-55.
130. Cancer Immunol Immunother. 2007 Jul;56(7):973-84. 
131. Vitam Horm. 2007;76:393-418.
132. Vitam Horm. 2011;86:179-215.
133. Zhonghua Yu Fang Yi Xue Za Zhi. 2003 Mar;37(2):112-4.
134. J Nutr. 1985 Jun;115(6):807-13.
135. Eur J Nutr. 2008 Oct;47(7):387-92.
136. Free Radic Biol Med. 2008 Mar 15;44(6):1203-8.
137. Proc Natl Acad Sci USA. 1997 Apr 1; 94(7):3217-22.
143. Atherosclerosis. 2005 May;180(1):19-25.
144. Ann N Y Acad Sci. 2004 Dec;1031:401-4.
145. Arch Pharm Res. 2008 Sep;31(9):1212-7.
146. Clinics (Sao Paulo). 2009;64(3):235-44.
147. J Atheroscler Thromb. 2010 Oct 27;17(10):1019-32.
148. Free Radic Biol Med. 2011 Sep 15;51(6):1164-74.
150. Wei Sheng Yan Jiu. 2004 Mar;33(2):243-5.
151. Mol Aspects Med. 2007 Oct-Dec;28(5-6):692-728.
152. Neuropharmacology. 2004 Nov;47(6):904-15.
153. Indian J Exp Biol. 2011 Oct;49(10):732-8.


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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.