5-LOX Inhibitor with ApresFlex by Life Extension offers a highly absorbable boswellia extract to help support and reduce the harmful effects of the body's inflammatory responses.
5-lipoxygenase (5-LOX) is a member of the lipoxygenase family of enzymes. It transforms fatty acids into leukotrienes. Excess levels of the enzyme 5-LOX sets in motion inflammatory responses that have been linked to common effects in aging individuals.70-74
Normal aging results in higher-than-desired levels of 5-LOX.
The typical American diet adds to the danger. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger overproduction of arachidonic acid. In response to high levels of arachidonic acid, the body produces the 5-LOX enzyme.
5-LOX breaks down arachidonic acid to pro-inflammatory compounds like leukotriene B4,75 a molecule that mediates attacks to joints, arterial walls, and other tissues. 5-LOX itself facilitates undesirable cell division changes. 76,77
The good news is that an extract of the Indian plant Boswellia serrata has been shown to neutralize 5-LOX. Used for centuries to help with inflammatory factors, boswellia acts as a natural 5-LOX inhibitor, intervening at the cellular level to block its unwanted effects. Confirmatory data reveal that a compound contained in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid)78,79 is the key to its beneficial action.
The problem is that boswellia is poorly absorbed into the blood.80 For this reason, a patent-pending, standardized form of boswellia called AprèsFlex® is being introduced. AprèsFlex® absorbs into the blood 52% more than previously available boswellia extracts.80
Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results may vary.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
ApresFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas – Laila Nutra LLC. U.S. Patent No. 8,551,496 and other patents pending.
Product & Usage Information:
Suggested Use: To inhibit the 5-lipoxygenase enzyme, take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.
Storage: Store in a cool dry place. Keep out of reach of children.
microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. Do not exceed recommended dose.
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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.