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ProHealth > Store Home > Bone & Joint Supplements > ProSAMe™

ProSAMe™ by ProHealth - 400 mg, 30 tablets

#PH150 - Sam-E Supplement - By ProHealth
$26.49 $41.95 SRP
You Save: $15.46 (37% Off)
SmartSavings Club   What's this?Free SmartSavings Auto Ship membership includes:
  • Better prices - up to 40% off regular pricing

  • Lower shipping cost - just $2.99! (Save $3 on each order)

  • Convenient Auto Ship the nutrients you need, shipped automatically on the schedule of your choice
Product Rating of 4.15 stars  
23 ratings
6 reviews  |  Write a Review
Order by 1pm PST M-F for same day shipping!
Product qualifies for $5.99 flat rate U.S. shipping.

Ease pain & brighten mood*

  • Helps promote positive moods*
  • Supports healthy joints*
  • Promotes healthy liver function*
Your Purchase Funds Research
A percentage of ProHealth profits are donated
directly to organizations focused on Chronic
Fatigue Syndrome and Fibromyalgia
research and advocacy. Learn more »

ProHealth FundraisingFunding Research to Find Cures
Knowing that research is the key to finding cures for chronic, debilitating diseases, ProHealth has raised and donated more than $3.5 million to organizations researching fibromyalgia, ME/Chronic Fatigue Syndrome and other conditions.

You Help Make it Possible
As a crucial part of our mission, a portion of each purchase you make goes toward this fundraising effort. This is such a high priority that in some years our donations outpaced our profits. Thank you for helping support our efforts.
SAM-e (S-adenosylmethionine) is an essential amino acid formed by the combination of ATP and methionine. As a molecule naturally produced in all living cells, it plays a key role in the biological process called methylation and, according to dozens of solid clinical trials:

  • Promotes formation of healthy cells and connective tissue, for healthy joints,

  • Helps with the synthesis of enzymes & detoxifying glutathione in the liver, for healthy liver function,

  • Plays a role in synthesis of various hormones & neurotransmitters, including serotonin, melatonin, dopamine and adrenaline,

  • And regulates the expression of genes, apparently helping to suppress errors in DNA replication.

ProSAMe™ delivers the natural benefits of SAM-e via enteric coated tablets to the small intestine, where it can be absorbed into the bloodstream.

SAM-e, Positive Mood, and Pain

Dopamine & serotonin are neurotransmitters that control mood & pain. When they are out of balance, you may feel blue; you may even be more susceptible to pain. ProSAMe™ promotes balanced levels of these important elements, so you feel better!

SAM-e and Healthy Joints

ProSAMe™ helps support cartilage-producing cells, keeping joints protected. It also promotes the cartilage molecules that retain water in the cells for enhanced joint flexibility & less pain. With ProSAMe™, you can be more active, whether it’s gardening or jogging you've been missing out on.

SAM-e and Healthy Liver Function

The compound structure of ProSAMe™ is actually one of the liver's own essential nutrients. ProSAMe™ supplementation produces glutathione for detoxification, while replenishing the liver's own SAMe.

Read more about ProSAMe™ in "SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood "

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

Write a Review

Product Rating of 5.0 stars
I have found ProSAME excellent . I suffer from anxiety disorder which has me gritting my teeth in my sleep I have tried many different thing but found this product really helpful .I noticed a difference within a few days.

Product Rating of 4.0 stars
Great product! I started feeling more energetic after only a couple weeks. Joints feel better too!

Product Rating of 5.0 stars
Takes awhile to get into your system, but after about one week you can really feel a difference in you mood and energy level.

Product Rating of 5.0 stars
Has made a huge difference in my mood and outlook. Tried on the advice of my physician and am very pleased.

Product Rating of 5.0 stars
I am going through perimenopause at age 42 and I have noticed it really effects my mood. Today I was feeling like every area of my life was doomed and had negative thoughts. I was reading how it helps with positive mood and I took one 400mg. tablet on my lunch break! I ...[read entire review]

Product Rating of 5.0 stars
This is excellent for depression and FMS pain. I had a clinical depression 40some years ago----depression runs in both sides of my family. I protect myself with taking the physician ordered antidepressant ALONG with SAM-E that is inherent in FMS. My doctor also approv ...[read entire review]


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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.