Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

How Your Gut Microbiome Influences Your Mental and Physical Health

High dose vitamin D3 supplementation lowers inflammatory T cells in multiple sclerosis patients

Chocolate's Potential Health Benefits – and its Effect on Chronic Fatigue Syndrome Patients

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Essential Oils - How and Where to Use Them

The Link Between Vitamin C And Optimal Immunity

What's So Great About Grape Seed?

Why Does Your Nose Run When It's Cold Outside?

SURVEY: What Is Your Diagnosis?

Study suggests that what you eat can influence how you sleep

 
Print Page
Email Article

Possible role of oxidative stress and immunological activation in mouse model of chronic fatigue syndrome and its attenuation by olive extract – Source: Journal of Neuroimmunology, May 26, 2010

  [ 63 votes ]   [ Discuss This Article ]
By Amit Gupta, et al. • www.ProHealth.com • June 14, 2010


[Note: Olive leaf extract  is derived from the fruit, leaves, bark and roots of the olive tree. The active ingredient – oleuropein – makes all parts of the tree strongly resistant to disease, insect damage, and other factors. A component of oleuropein – elenoic acid – has been shown to support the body’s immune defense systems. In a previous paper, this team of pharmacologists & microbiologists reported the “significant antioxidative” effect of curcumin (turmeric) - another complex polyphenolic antioxidant compound - in an animal model of chronic fatigue syndrome.]
 
Various putative theories involved in the development of chronic fatigue syndrome revolve around the role of stress, infection and oxidative stress [free radical damage to cells]. Scientific evidence highlighting the protective role of nutritional supplements in chronic fatigue syndrome is lacking.

Based on these assumptions, the present study was designed to evaluate the effect of olive extract in a mouse model of immunologically-induced fatigue, wherein purified lipopolysaccharide (LPS) and Brucella abortus (BA) antigen were used as immunogens.

The assessment of chronic fatigue syndrome was based on immobility period during chronic water-immersion stress test for 10 min daily. The stress-induced hyperalgesia was measured by tail withdrawal latency. Mice challenged with LPS or BA for 19 days showed significant increase in the immobility time, hyperalgesia and oxidative stress on the 19th day.

Serum tumor necrosis factor-alpha (TNF-a) levels were also markedly increased with LPS or BA challenge.

Concurrent treatment with olive extract resulted in a significant decrease in the immobility time as well as hyperalgesia. There was significant attenuation of oxidative stress as well as serum TNF-a levels. The results of the present study:

• Strongly indicate the role of oxidative stress and immunological activation in the pathophysiology of chronic fatigue syndrome

• And highlight the valuable role of olive extract in combating chronic fatigue syndrome.

Source: Journal of Neuroimmunology, May 26, 2010. PMID: 20537729, by Gupta A, Vij G, Chopra K. Pharmacology Division, University Institute of Pharmaceutical Sciences, UGC Center of Advanced Study, Panjab University, Chandigarh, India. [Email: dr_chopra_k@yahoo.com]





Post a Comment

Featured Products From the ProHealth Store
Curcumin, Longvida™ Vitamin D3 Extreme™ FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

How Glutathione Can Save Your Life

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Olive Leaf Extract (15% Oleuropein) Olive Leaf Extract (15% Oleuropein)
Potent Immune Support and Antioxidant Protection
Curcumin, Longvida™ Curcumin, Longvida™
Helps Support Cognition, Memory & Overall Health
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
Clinically Studied Joint Relief Product for FM & ME/CFS Clinically Studied Joint Relief Product for FM & ME/CFS

FIBROMYALGIA
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
LYME DISEASE
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
FORUMS
Fibromyalgia
M.E. & CFS
Lyme Disease
General Health
WHOLESALE
AFFILIATES GUARANTEE
PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing