Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Big step towards cure for HIV and other lifelong viral infections

SURVEY RESULTS: Attitudes About Fatigue

Superfood Trio: Ginger, Turmeric, and Carrots?

Rejuvenate Your Skin Naturally With Sea Buckthorn Oil

Can Drinking More Water Help You Lose Weight?

Resveratrol’s Link to Slowing Alzheimer’s

Tropical Turmeric Carrot Juice & Smoothie

Most Everyone Can Use More Vitamin D

Greater intake of dietary omega-3 fatty acids associated with lower risk of diabetic retinopathy

Omega-3s May Improve Healing After a Heart Attack

 
Print Page
Email Article

Possible role of oxidative stress and immunological activation in mouse model of chronic fatigue syndrome and its attenuation by olive extract – Source: Journal of Neuroimmunology, May 26, 2010

  [ 63 votes ]   [ Discuss This Article ]
By Amit Gupta, et al. • www.ProHealth.com • June 14, 2010


[Note: Olive leaf extract  is derived from the fruit, leaves, bark and roots of the olive tree. The active ingredient – oleuropein – makes all parts of the tree strongly resistant to disease, insect damage, and other factors. A component of oleuropein – elenoic acid – has been shown to support the body’s immune defense systems. In a previous paper, this team of pharmacologists & microbiologists reported the “significant antioxidative” effect of curcumin (turmeric) - another complex polyphenolic antioxidant compound - in an animal model of chronic fatigue syndrome.]
 
Various putative theories involved in the development of chronic fatigue syndrome revolve around the role of stress, infection and oxidative stress [free radical damage to cells]. Scientific evidence highlighting the protective role of nutritional supplements in chronic fatigue syndrome is lacking.

Based on these assumptions, the present study was designed to evaluate the effect of olive extract in a mouse model of immunologically-induced fatigue, wherein purified lipopolysaccharide (LPS) and Brucella abortus (BA) antigen were used as immunogens.

The assessment of chronic fatigue syndrome was based on immobility period during chronic water-immersion stress test for 10 min daily. The stress-induced hyperalgesia was measured by tail withdrawal latency. Mice challenged with LPS or BA for 19 days showed significant increase in the immobility time, hyperalgesia and oxidative stress on the 19th day.

Serum tumor necrosis factor-alpha (TNF-a) levels were also markedly increased with LPS or BA challenge.

Concurrent treatment with olive extract resulted in a significant decrease in the immobility time as well as hyperalgesia. There was significant attenuation of oxidative stress as well as serum TNF-a levels. The results of the present study:

• Strongly indicate the role of oxidative stress and immunological activation in the pathophysiology of chronic fatigue syndrome

• And highlight the valuable role of olive extract in combating chronic fatigue syndrome.

Source: Journal of Neuroimmunology, May 26, 2010. PMID: 20537729, by Gupta A, Vij G, Chopra K. Pharmacology Division, University Institute of Pharmaceutical Sciences, UGC Center of Advanced Study, Panjab University, Chandigarh, India. [Email: dr_chopra_k@yahoo.com]





Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Curcumin, Longvida™ Olive Leaf Extract (15% Oleuropein)

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Olive Leaf Extract (15% Oleuropein) Olive Leaf Extract (15% Oleuropein)
Potent Immune Support and Antioxidant Protection
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Curcumin, Longvida™ Curcumin, Longvida™
Helps Support Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Vitamin E: Super Antioxidant We Only Thought We Knew Vitamin E: Super Antioxidant We Only Thought We Knew

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map