ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial

Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?

Exploring the association between Morgellons disease and Lyme disease: identification of Borrelia bu...

Lyme Disease Activists Take Fight to Washington D.C.

New Envita Study Shows Chronic Lyme Disease "Fools" Immune System, Resistant to Antibiotics

Safely Burn Away Body Fat

Omega-3 fatty acids boost B vitamin brain benefit

Substantial health threat: Never-before-seen tick-borne disease

Lyme Advocates Call on IDSA to Focus on Patient Care Instead of Attacking Those in Distress

Zinc deficiency linked to chronic inflammation

 
Print Page
Email Article

Study of Morphine/Naltrexone Drug for Chronic Pain Recruiting at 124 US Primary Care Sites

  [ 13 votes ]   [ 1 Comment ]
www.ProHealth.com • December 9, 2010


The "Conversion to Embeda® With Rescue Trial (ConvERT)" - Clinical Trials.gov identifier NCT01179191 - is recruiting participants at 124 study locations in more than 30 states.

Primary care provider research sites are recruiting about 1,300 individuals age 21 and older who have been taking a ‘round the clock’ opioid medication for at least 30 days for chonic moderate to severe pain of at least 3 months' duration.

Specifically:

“The purpose of the research study is to find out if opioid dependent chronic pain patients who are judged by their physician to be eligible to change their current opioid medicine and to participate in this study can be successfully adjusted to a stable dose of EMBEDA® (morphine sulfate and naltrexone hydrochloride). The study will also assess each patient's risk for prescription opioid abuse, misuse and diversion.”

Note: Embeda is essentially a product designed to allow extended-release of morphine while preventing abuse of the drug. Pellets of morphine and naltrexone (which counteracts morphine's effect) are embedded in the pill. The morphine is timed to release over time so as to keep the level of morphine at a steady level around the clock, while the naltrexone pellets are designed to pass through the GI tract unabsorbed. The concept is that, while biting down on, crushing or dissolving & ingesting a pill containing only pure morphine would release all the morphine at the same time, creating a heightened immediate effect (potentially opioid abuse); if the naltrexone pellets are also crushed, all the naltrexone will also be released at the same time and counteract the opioid’s effect. This trial seems designed to determine the extent to which or under what circumstances primary care physicians may prescribe Embeda to their pain patients without significant risk of opioid abuse.

To read more about the study, the inclusion/exclusion criteria, and study site locations & contact information, go to the trial's ClinicalTrials.gov listing at http://clinicaltrials.gov/ct2/show/study/NCT01179191#locn



Please Discuss This Article:   Post a Comment 

naltrexone
Posted by: simonedb
Dec 9, 2010
this is confusing to me as when I tried LDN and still had small amount of propoxyphene in my system, the LDN way increased my pain and gave me killer headaches, it blocked the pain numbing aspect of propoxyphene. I have heard of people getting strokes too from being given naltrexone when an opioid wasnt totally out of their system as it induced dangerous w/drawal, wonder how they could pull this off, seems like trying to find a way to get someone on antabuse to drink alcohol simultaneously. And heaven forbid if someone in pain should have pleasant side effects from their medication, we can't allow that, they should suffer eh.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
How Glutathione Can Save Your Life How Glutathione Can Save Your Life

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing