ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Vitamin D Deficiency Linked to Neurological Diseases; Also Raises Risk of Asthma Attacks, and More

7 Best Foods You Can Eat

Study: Doubling saturated fat in the diet does not increase saturated fat in blood

The Gut Microbiome and the Brain

Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed

CoQ10 supplementation reduces statin-related muscle pain in randomized trial

Controlling obesity with potato extract

Plant used in traditional Chinese medicine may treat metabolic diseases and obesity

Natural Gut Viruses Join Bacterial “Cousins” in Maintaining Health and Fighting Infections

Proton pump inhibitors decrease diversity in gut microbiome, increase risk for complications

 
Print Page
Email Article

Many FM & ME/CFS patients in D-ribose study report quality of life improvements

  [ 1379 votes ]   [ 2 Comments ]
www.ProHealth.com • December 6, 2008


The natural dietary supplement D-ribose - a form of sugar essential to fuel cellular energy generation - "significantly reduced clinical symptoms in patients suffering from Fibromyalgia and Chronic Fatigue Syndrome," a Texas-based research group reported.

Their study - "The Use of D-Ribose in Chronic Fatigue Syndrome and Fibromyalgia" - headed by internationally recognized FM/CFS Doctor Jacob Teitelbaum, MD, was published in the November 2006 issue of the Journal of Alternative and Complementary Medicine.*

Key Findings

Of 41 study participants diagnosed with ME/CFS and/or FM who received D-ribose supplementation daily for four weeks, 66 percent achieved “significant improvements in quality of life," the report states. Change was measured using patients' before-and-after visual analog scale (VAS) scores for energy, sleep, mental clarity, pain intensity, and well-being, as well as global quality of life assessments.

Key findings for the patients who perceived significant change included:

• 45 percent average improvement in energy score

• 30 percent average improvement in overall well-being

These findings are considered statistically significant (P < 0.0001), meaning the probability they were owing to chance is less than 1 in 1,000. In particular, the report indicates, patients tended to perceive improved "ability to overcome fatigue," as well as less muscle soreness and stiffness. And supplementation with the natural substance D-ribose was "tolerated well."

Study Details

The study was open label and uncontrolled, meaning all participants took D-ribose, no patients were given a placebo, or "fake" dose as a means of comparison, and no subjects with normal health were included as a means of comparison. Termed a "feasibility" study, the research involved a small number of patients, as a possible preliminary to more extensive investigation. Of the 41 patients, 78 percent were female and their average age was 48. They took five grams of D-ribose by mouth three times a day for an average of 28 days.

What is D-ribose?

D-ribose, also called “ribose,” is a form of sugar containing five carbon atoms that all living cells require for creation of ATP (adenosine triphosphate), the body's main source of energy. D-ribose is also a crucial component of other important molecules within our cells, such as RNA (ribonucleic acid), and DNA (deoxynbonucleic acid). DNA produces the proteins cells need to function and develop, while RNA provides the instructions for the job.

How is D-ribose Obtained?

Our bodies make D-ribose for use by the cells from glucose - a sugar that contains six carbon atoms, which plants manufacture by the process of photosynthesis. We obtain glucose, also known as "blood sugar," from the fruits, berries, vegetables, and honey we eat. In a glucose-deficient pinch - such as starvation, fasting, or extremely demanding exercise - our liver and even our kidneys may also synthesize glucose from other compounds to provide a source of D-ribose for the cells. But this is an energy-intensive process.

D-ribose has also long been available as a dietary supplement, produced by fermentation of corn syrup. And it can be obtained from some RNA-rich food substances such as brewer's yeast.

What's the Theory of Benefit?

How do the researchers think D-ribose supplementation supports improved ME/CFS and FM patient quality of life? Many scientists have come to believe that "inefficient" or "disordered" cellular metabolism may account for the symptoms of fatigue and muscle pain associated with ME/CFS and FM.

Patients' muscles become "anaerobic" or depleted of oxygen faster than the muscles of normal healthy people. And supplementation with the nutrient D-ribose may represent one avenue for supporting faster regeneration of ATP and healthier metabolism in oxygen-deprived muscle cells.

_______

* To review an abstract of the study report, go to http://www.immunesupport.com/library/showarticle.cfm/id/7539

Note: This information has not been evaluated by the FDA. It is not meant to diagnose, treat, cure, or prevent any illness, disease, or condition. It is very important that you never make any change in your health support plan or regimen without reviewing and discussing it collaboratively with your professional healthcare team.



Please Discuss This Article:   Post a Comment 

D-Ribose
Posted by: jweismann
Dec 6, 2006
i found this article most interesting, as i tried D-ribose as a powdered supplement about 2 years ago & really felt it helped w/energy & muscles not getting so fatigued, but was unable to afford to continue it's use. Although caffiene is a big fibro trigger for me, i occasionally need it anyway! i discovered the energy drink MDX made by Mountain Dew contains D-ribose and it is the ONLY one that not only does not make me jittery at all, but it also does not trigger fibro symptoms, nor keep nme awake. I only use it a few times a month, so perhaps regular use would aggravate things due to the caffiene, but i'm very pleased thus far!! as an aside, i have been almost symptom free for 18 months by using a sudafed/guafenisen/dextromethorthan (sp??) cold tablet every day....not exactly following the protocol recommended on this site, but after 17 years since diagnosis, i'm thrilled & pretty convinced this is why.
Reply Reply

 
D-ribose and hypoglycemia
Posted by: meditationlotus
Dec 17, 2006
How does d-ribose work if you have hypoglycemia? I have hypoglycemia and tried d-ribose, and it seems like i felt worse, but you never know for sure what is causing a symptom. Is there any info about taking d-ribose if you have hypoglycemia? I emailed endfatigue.com about it, but no one responded.

 

 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
A Breakthrough for Mitochondrial Dysfunction A Breakthrough for Mitochondrial Dysfunction
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing