ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Black Tea Is Great for Your Gut

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Mint: Learn More About This Refreshing and Invigorating Herb

Give Your Health a Much-Needed Boost With Geranium

 
Print Page
Email Article

Gut Inflammation in Chronic Fatigue Syndrome – Source: Nutrition & Metabolism, Oct 12, 2010

  [ 19 votes ]   [ Discuss This Article ]
By Shaheen E Lakhan, Annette Kirchgessner • www.ProHealth.com • October 13, 2010


[Note: To read the free full text of this excellent article, which pulls together the most recent science to propose that therapeutic efforts to modify gut bacteria and the effects of pathogens on the gut mucosal barrier/enteric nerves "could be a means to modulate the development and/or progression of this disorder,” click HERE.]

Chronic fatigue syndrome (CFS) is a debilitating disease characterized by unexplained disabling fatigue and a combination of accompanying symptoms the pathology of which is incompletely understood.

Many CFS patients complain of gut dysfunction. In fact, patients with CFS are more likely to report a previous diagnosis of irritable bowel syndrome (IBS), a common functional disorder of the gut, and experience IBS-related symptoms.

Recently, evidence for interactions between the intestinal microbiota, mucosal barrier function, and the immune system have been shown to play a role in the disorder's pathogenesis.

Studies examining the microecology of the gastrointestinal (GI) tract have identified specific microorganisms whose presence appears related to disease;

In CFS,

• A role for altered intestinal microbiota in the pathogenesis of the disease has recently been suggested.

• Mucosal barrier dysfunction promoting bacterial translocation has also been observed.

• Finally, an altered mucosal immune system has been associated with the disease.

In this article, we discuss the interplay between these factors in CFS and how they could play a significant role in GI dysfunction by modulating the activity of the enteric nervous system, the intrinsic innervation of the gut.

If an altered intestinal microbiota, mucosal barrier dysfunction, and aberrant intestinal immunity contribute to the pathogenesis of CFS, therapeutic efforts to modify gut microbiota could be a means to modulate the development and/or progression of this disorder.

For example, the administration of probiotics* could:

• Alter the gut microbiota,

• Improve mucosal barrier function,

• Decrease pro-inflammatory cytokines,

• And have the potential to positively influence mood in patients where both emotional symptoms and inflammatory immune signals are elevated.

Probiotics also have the potential to improve gut motility, which is dysfunctional in many CFS patients.

Source: Nutrition & Metabolism, Oct 12, 2010. DOI:10.1186/1743-7075-7-79, by Lakhan SE, Kirchgessner A. Global Neuroscience Initiative Foundation, Los Angeles, CA, USA. [Email: slakhan@gnif.org or akirchgessner@gnif.org]

___
* Note: The article highlights a great deal of research regarding the benefits of ‘probiotics’ such as the Bifidobacteria and Lactobacillus species of bacteria, and potentially of CoQ10, in support of reduced gut inflammation/tissue damage caused by gut pathogens.





Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Vitamin D3 Extreme™ Coenzyme Q10 (CoQ10) with Vitamin E


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Acidophilus Pearls Acidophilus Pearls
Guaranteed active cultures for better digestion
Coenzyme Q10 (CoQ10) with Vitamin E Coenzyme Q10 (CoQ10) with Vitamin E
Top Energy & Heart Support Nutrient
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery
"It's Not Easy Being Green" - But It Is Healthy
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map