ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Print Page
Email Article

Gluten associated GI inflammation? GF sourdoughs may hasten healing

  [ 28 votes ]   [ 1 Comment ] • March 1, 2012

previous article next article

“The sourdough fermentation may enhance the recovery from intestinal inflammation of celiac patients at the early stage of the gluten-free diet”
– Source: European Journal of Nutrition, Feb 4, 2012

By Maria Calasso, et al.

Purpose: This study aimed at investigating the effect of corn, rice and amaranth gluten-free (GF) sourdoughs on the release of nitric oxide (NO) and synthesis of pro-inflammatory cytokines by duodenal mucosa biopsies of eight celiac disease (CD) patients. [Elevated nitric oxide production has been associated with mucosal inflammation in celiac patients.]

Methods: Selected lactic acid bacteria were used as starters for the manufacture of corn, rice or amaranth sourdoughs.

Chemically acidified doughs, without bacterial starters, and doughs started with baker's yeast alone were also manufactured from the same gluten-free matrices.

Pepsin-trypsin (PT) digests were produced from all sourdoughs and doughs, and used to assay the rate of recovery of biopsy specimens from eight CD patients at diagnosis.

The release of nitric oxide and the synthesis of pro-inflammatory cytokines interferon-gamma (IFN-y) were assayed.

During fermentation, lactic acid bacteria acidified and grew well (ca. log 9.0 CFU/g) on all gluten-free matrices, showing intense proteolysis [digestion of protein into simpler, soluble substances].

Duodenal biopsy specimens still released nitric oxide and IFN-y when subjected to treatments with basal medium (control), PT-digest from chemically acidified doughs, and PT-digest from doughs fermented with baker's yeast alone.

On the contrary, the treatment of all the biopsy specimens with PT-digests from all gluten-free matrices subjected to sourdough fermentation significantly decreased:

• The release of nitric oxide,

• And the synthesis of pro-inflammatory interferon-gamma (IFN-y).

During manufacture of gluten-free baked goods, the use of sourdough fermentation could be considered as an adjuvant to enhance the recovery from intestinal inflammation of coeliac patients at the early stage of the gluten-free diet.

Source: European Journal of Nutrition, Feb 4, 2012. PMID:22307223, by Calasso M, Vincentini O, Valitutti F, Felli C, Gobbetti M, Di Cagno R. Department of Biologia e Chimica Agro-Forestale ed Ambientale, University of Bari, Bari, Italy.

previous article
  Rating 3.7 (28 votes) next article

DISCUSS THIS ARTICLE   (1 existing comment) Post a Comment 

Petition for gluten free and allergen free Girl Scout cookies
Posted by: StacyIM
Mar 2, 2012
Please support my petition for the Girl Scouts to sell a gluten free and allergen free cookie.
Reply Reply
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Natural Resveratrol Natural Resveratrol
Powerful Antioxidant Support + Positive Anti-aging Effects
Vitamin D3 5000 IU Vitamin D3 5000 IU
Give your body a boost with the sunshine vitamin
Omega 3-6-9 Omega 3-6-9
All three EFAs in one convenient form

Most Viewed Articles
What's the Hidden Cause Behind YOUR Fibromyalgia Flares? [more]

Pridgen Reports Fibromyalgia Antiviral Trial Results “Very Positive”: Predicts New Approach Will Be ... [more]

Massage Therapy Studies for Fibromyalgia Reviewed [more]

How to Limit or Minimize Your Fibromyalgia Flare [more]

Mitochondrial Dysfunction, Post-Exertional Malaise and CFS/ME [more]

The Devil Is In The Details – A Herpes Simplex Virus Inquiry For Fibromyalgia and Chronic Fatigue Sy... [more]

Sympathetic Nervous System Dysfunction in FIbromyalgia and Overlapping Conditions [more]

Review of Nutritional Supplements Used for ME/CFS and FM [more]

VIDEO: Mom Needs to Lie Down [more]

FREE: Spring Volume of Broken Body, Wounded Spirit – March 22, 2014 [more]

What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing