ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Meta-analysis adds evidence to association between omega-3 supplementation and lower heart rate

Friendly User's Guide for the Timing of Nutritional Supplements

The Health Benefits of Manuka Honey

Increase Your Magnesium Intake

Love Your Lungs With Tomatoes and Apples

How to Get Rid of Stretch Marks Naturally

Top Tips to Boost Your Immunity

Essential Oils Lower Blood Pressure

Vitamin D supplementation could ease IBS symptoms

11 Amazing Health Benefits of Using Baking Soda

 
Print Page
Email Article

Clinical research networks: A step towards evidence-based practice in pediatric rheumatology

  [ 172 votes ]   [ Discuss This Article ]
By Elizabeth D Mellins and Lisa G Rider • www.ProHealth.com • February 7, 2007


Journal: Nature Clinical Practice Rheumatology. (2007) 3, 59

Authors: Elizabeth D Mellins, Lisa G Rider

DOI:10.1038/ncprheum0405

[Article has no abstract. Opening text supplied instead.]

Pediatric rheumatologists are often forced to make clinical decisions in the absence of robust evidence about the most effective therapies for their patients. A number of factors have contributed to the relative lack of practice-guiding information.

n Of an estimated 200,000 children with rheumatic diseases in the U.S. about 30 percent are under the care of pediatric rheumatologists, and it is likely that an equal number see adult rheumatologists (Mayer ML et al. [2003] Arthritis Rheum 49: 759–765).

n With this dispersion of a relatively small patient population, adequately-powered studies can rarely be accomplished at a single site.

n The number of investigators appropriately positioned to carry out clinical research in pediatric rheumatology is also small. In total, there are 215 board-certified pediatric rheumatologists in the U.S.; 13 states don't have a pediatric rheumatologist at all.

n Many pediatric rheumatologists are 'one-person divisions' with substantial clinical responsibility.

n In addition to these barriers to investigator-initiated studies, pharmaceutical companies have historically seen the pediatric rheumatology population as unattractively small or too high risk.

n FDA policies to stimulate studies in children apply to pediatric forms of non-orphan diseases; only polyarticular juvenile idiopathic arthritis (JIA) qualifies and has benefited from increased industry-sponsored trials.





Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™ Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get Energized with Malic Acid & Magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire
Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health
Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map