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Effects of Topical O24 Essential Oils on Patients with Fibromyalgia Syndrome: A Randomized, Placebo Controlled Pilot Study

  [ 463 votes ]   [ 1 Comment ]
By Gordon D. Ko, et al. • • March 14, 2007

[Note: O24R is a clinically-tested over-the-counter plant oil mixture including camphor that is applied topically (to the skin).]

Journal: Journal of Musculoskeletal Pain. 2007. Vol. 15, #1, pp. 11-19 [E-publication ahead of print]

Authors and affiliations: Ko GD, Hum A, Traitses G, Berbrayer D. Department of Rehabilitative Medicine, University of Toronto, Sunnybrook Health Sciences Centre, Markham, Ontario, Canada (Ko and Berbrayer); Canadian Centre Integrative Medicine, Burn Trauma Clinic, University of Toronto, St. John's Rehabilitation Hospital, Toronto, ON, Canada (Hum, Traitses). [E-mail: ]

DOI: 10.1300/J094v15n01_03

Objectives: To review the literature on topical pain management in Fibromyalgia [FMS] and to report on effective treatment with topical O24 essential oils.

Methods: Following a literature review of MEDLINE and EMBASE for published randomized controlled trials on topical therapies for FMS pain treatment, a double-blinded placebo controlled trial was carried out in outpatient clinics on 153 subjects meeting the American College of Rheumatology criteria for FMS using topical O24 essential oils for a treatment period of one month.

Main outcome measures were pain visual analog scale ratings, a diary, the Fibromyalgia Impact Questionnaire, Jamar grip strength, pressure algometry measurements of tender point [TeP] pain threshold, and seven-point Lanier scale rating of treatment.

Results: In the 133 participants with complete data, improvements were noted in the visual analog scale night pain rating (P = 0.018), Jamar grip strength (P < 0.001), number of TePs (P < 0.001) and average TeP pain threshold (P < 0.001), and the Lanier scale (P = 0.001) with topical O24 over the placebo. [P < 0.001 means ‘probability’ that this result would occur by chance is less than 1 in 100]

Conclusion: This pilot randomized controlled trial suggests that FMS patients may be effectively managed for pain with topical O24. This would need to be confirmed with larger and longer randomized controlled trials. The topical O24 essential oils appear to have a clinically important effect in FMS.

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Article Comments Post a Comment

Topical O24 oils
Posted by: r47mb
Mar 21, 2007
Fibro O24 is the only thing that I have tried that even remotely helped, but at $20.00 for 1 oz. is absolutely ridiculous! It only lasts a few days! Sorry, but it figures! I live on Welfare and am in my sixth year of my disability fight, ready to file for the final Civil court fight! Just can not afford it!
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