ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Lilac Oil: More Than Just for Fragrance

Eat More Yogurt and Avoid Osteoporosis

Safflower: An Economically Important Herb That Can Benefit Humans and Animals Alike

What Is Bilberry Good For?

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Resveratrol Improves Arteries

Higher omega 3 levels linked to improved brain blood flow

 
Print Page
Email Article

Growth hormone as concomitant treatment in severe Fibromyalgia associated with low IGF-1 serum levels. A pilot study - Source: BMC Musculoskeletal Disorders, Nov 30, 2007

  [ 108 votes ]   [ 1 Comment ]
By Guillem Cuatrecasas, MD, et al. • www.ProHealth.com • December 8, 2007


[Note: The full text of this article is available free of charge at http://www.biomedcentral.com/content/pdf/1471-2474-8-119.pdf ]

Background: There is evidence of functional growth hormone (GH) deficiency, expressed by means of low insulin-like growth factor 1 (IGF-1) serum levels, in a subset of fibromyalgia patients. The efficacy of GH versus placebo has been previously suggested in this population. We investigated the efficacy and safety of low dose GH as an adjunct to standard therapy in the treatment of severe, prolonged and well-treated fibromyalgia patients with low IGF-1 levels.

Methods: Twenty-four patients were enrolled in a randomized, open-label, best available care-controlled study. Patients were randomly assigned to receive either 0.0125 mg/kg/d of GH subcutaneously (titrated depending on IGF-1) added to standard therapy or standard therapy alone during one year. The number of tender points, the Fibromyalgia Impact Questionnaire (FIQ) and the EuroQol 5D (EQ-5D), including a Quality of Life visual analogic scale (EQ-VAS) were assessed at different time-points.

Results:

  • At the end of the study, the GH group showed a 60% reduction in the mean number of tender points (pairs) compared to the control group (p<0.05; 3.25+/-0.8 vs. 8.25+/-0.9).
  • Similar improvements were observed in FIQ score (p<0.05) and EQ-VAS scale (p<0.001).
  • There was a prompt response to GH administration, with most patients showing improvement within the first months in most of the outcomes.
  • The concomitant administration of GH and standard therapy was well tolerated, and no patients discontinued the study due to adverse events.
  • Conclusions: The present findings indicate the advantage of adding a daily GH dose to the standard therapy in a subset of severe fibromyalgia patients with low IGF-1 serum levels.

    Trial Registration: NCT00497562 (ClinicalTrials.gov).

    Source: BMC Musculoskeletal Disorders. 2007 Nov 30;8(1):119 [E-pub ahead of print] PMID: 18053120, by Cuatrecasas G, Riudavets C, Guell MA, Nadal A. Servicio de Endocrinología, Centro Médico Teknon, Barcelona, Spain. [E-mail: Guillem Cuatrecasas, MD, endocrinologia@teknon.es]





    Post a Comment

    Featured Products From the ProHealth Store
    Vitamin D3 Extreme™ Ultra EPA  - Fish Oil Optimized Curcumin Longvida®

    Looking for Vitamins, Herbs and Supplements?
    Search the ProHealth Store for Hundreds of Natural Health Products


    Article Comments Post a Comment

    Growth Hormone Study
    Posted by: brighteyestish
    Dec 19, 2007
    I was in a 6 month study with a oral growth hormone and It did very well. It took 3-4 months before I started to stop hurting. At the end of the study My tender points not longer hurt...AT ALL. Now that I am off of it I feel sluggish and drained. I hope they put it on the market.
    Reply Reply
     
    NAD+ Ignite with Niagen

    Featured Products

    Ultra ATP+, Double Strength Ultra ATP+, Double Strength
    Get energized with malic acid & magnesium
    Vitamin D3 Extreme™ Vitamin D3 Extreme™
    50,000 IU Vitamin D3 - Prescription Strength
    Energy NADH™ 12.5mg Energy NADH™ 12.5mg
    Improve Energy & Cognitive Function
    FibroSleep™ FibroSleep™
    The All-in-One Natural Sleep Aid
    Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
    Ultra concentrated source of essential fish oils

    Natural Remedies

    More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
    Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
    The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
    When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
    Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket

    CONTACT US
    ProHealth, Inc.
    555 Maple Ave
    Carpinteria, CA 93013
    (800) 366-6056  |  Email

    · Become a Wholesaler
    · Vendor Inquiries
    · Affiliate Program
    SHOP WITH CONFIDENCE
    Credit Card Processing
    SUBSCRIBE TO OUR NEWSLETTERS
    Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

    CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

    © 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map