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Is Chronic Fatigue Syndrome caused by a rare brain infection of a common, normally benign virus? - Source: Medical Hypotheses, Apr 24 2008

  [ 37 votes ]   [ 5 Comments ]
By Bjorn Grinde • www.ProHealth.com • April 29, 2008


Chronic fatigue syndrome (CFS) is a disabling disease of unknown aetiology. A variety of factors have been suggested as possible causes. Although the symptoms and clinical findings are heterogeneous, the syndrome is sufficiently distinct, at least in relation to the more obvious cases, that a common explanation seems likely.

In this paper, it is proposed that the disease is caused by a ubiquitous, but normally benign virus, e.g., one of the circoviruses.

Circoviruses are chronically present in a majority of people, but are rarely tested for diagnostically. Normally these viruses do not penetrate the blood-brain barrier, but exceptions have been reported, and related viruses cause disease in the central nervous system of animals.

The flu-like illness that often precedes the onset of CFS may either suppress immune function, causing an increased viremia, and/or lower the blood-brain barrier. In both cases the result may be that a virus already present in the blood enters the brain.

It is well known that zoonotic viruses typically are more malignant than viruses with a long history of host-virus evolution. Similarly, a virus reaching an unfamiliar organ may cause particular problems.

[Note: For more information see "An Interesting Hypothesis" by CFIDS Association Director Suzanne Vernon, PhD.]

Source: Medical Hypotheses, Apr 24 2008 [E-publication ahead of print] PMID: 18440157, by Grinde B. National Institute of Public Health, Nydalen, Oslo, Norway.





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Article Comments Post a Comment

viruses entering the brain
Posted by: guaima
May 2, 2008
Just a few things I have noticed in having fibro.... About 4 years ago I had an MRI, and it was different than normal, but the Dr. didn't comment on it other than saying I had a larger space area in the frontal lobe. Virus?, Maybe? Then last year I had a massive dose of antibiotics before my knee replacement. After my surgery I felt 100% better....better than I'd been in years!! Why was my pain, fatigue and fibrofog gone? I was DANCING in the halls of the hospital and told to quit because the cement in my knee wasn't hardened yet! I want that feeling back! Has anyone else had this experience? Guaima-Sherrill In Iowa
Reply Reply

 
Do you get the same effect from an saline IV ?
Posted by: turtlecurls
May 23, 2008
Us CFS folks are dehydrated and often with less blood volume than normal. IVs can make you feel much better for a few days (although rare to completely recover.)

So if it's not from the IV, it's VERY interesting news. Is there a way for you to find out?

If is from the IV, you may be able to fix your problems even if you aren't recovered!

If it's not the IV, what else could it have been? Deep sleep with the anethesia? Cortisol shot? Anti-biotics for constant elevation of infection in CFS body because our systems don't fight things well.

I'll keep coming back to see if you've figured it out. For yourself certainly a single intense run of AB seems a worthwhile test!

 

 
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