ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

16 Tips from 16 Years Sick

On-and-off fasting helps fight obesity, study finds

Fibromyalgia Fare Fit for All Seasons

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Higher vitamin D levels associated with less severe disease in NAFLD patients

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

How zinc helps fight esophageal cancer

Low vitamin D levels predict ED in diabetics

What Benefits Can You Get From High-Quality Whey Protein?

 
Print Page
Email Article

Ventricular cerebrospinal fluid lactate is increased in chronic fatigue syndrome compared with generalized anxiety disorder: an in vivo 3.0 T (1)H MRS imaging study - Source: NMR in Biomedicine, Oct 21, 2008

  [ 6 votes ]   [ 1 Comment ]
By Sanjay J Mathew, Dikoma C Shungu, et al. • www.ProHealth.com • October 25, 2008


[Note: lactate - or lactic acid - forms when the cells break down carbohydrates to use for energy when oxygen supply is low (anaerobic vs. aerobic energy conversion).]

Chronic fatigue syndrome (CFS) is a controversial diagnosis because of the lack of biomarkers for the illness and its symptom overlap with neuropsychiatric, infectious, and rheumatological disorders.

We compared lateral ventricular volumes derived from tissue-segmented T(1)-weighted volumetric MRI data and cerebrospinal fluid (CSF) lactate concentrations measured by proton MRS imaging ((1)H MRSI) in 16 subjects with CFS (modified US Centers for Disease Control and Prevention criteria) with those in 14 patients with generalized anxiety disorder (GAD) and in 15 healthy volunteers, matched group-wise for age, sex, body mass index, handedness, and IQ.

Mean lateral ventricular lactate concentrations measured by (1)H MRSI:

• In CFS were increased by 297% compared with those in generalized anxiety disorder (P < 0.001)

• And by 348% compared with those in healthy volunteers (P < 0.001), ….

…even after controlling for ventricular volume, which did not differ significantly between the groups.

Regression analysis revealed that diagnosis accounted for 43% of the variance in ventricular lactate.

CFS is associated with significantly raised concentrations of ventricular lactate, potentially consistent with recent evidence of decreased cortical blood flow, secondary mitochondrial dysfunction, and/or oxidative stress abnormalities in the disorder.

Source: NMR in Biomedicine, Oct 21, 2008. E-pub ahead of print. PMID: 18942064, by Mathew SJ, Mao X, Keegan KA, Levine SM, Smith EL, Heier LA, Otcheretko V, Coplan JD, Shungu DC. Department of Psychiatry, Mount Sinai School of Medicine, New York; Department of Radiology, Weill Medical College of Cornell University, New York; Private Practice, Infectious Disease/Internal Medicine, New York; Department of Psychiatry, Downstate Medical Center, Brooklyn, New York, USA. E-mail: Dikoma C. Shungu dcs7001@med.cornell.edu





Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®


Article Comments Post a Comment

Lactic Acid and EMR
Posted by: doyon.paul
Jun 13, 2010
During the action of a uhf electromagnetic field with a frequency of 48 MHz and of nonthermogenic intensity, the concentration of lactic and pyruvic acids in the rat brain tissue rises while the glycogen content falls. These effects are dependent on the intensity of the field and the duration of its action. In the case of prolonged exposure to a field of intensity 800 W/m, the lactic acid concentration in the brain remains elevated one month after the end of exposure. http://www.springerlink.com/content/p82g232233685635/fulltext.pdf
Reply Reply
 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera
Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map