Activate Now
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

'Healthy' Foods Differ by Individual

Surprising Benefits of Cinnamon

Specific vitamin D levels linked to heart problems

A Sleep Intervention For Children With Autism: A Pilot Study

Higher vitamin D levels may be protective against acute rhinosinusitis

Basic Vitamin A Primer

Curcumin: The All In One Solution

Coconut oil can control overgrowth of a fungal pathogen in GI tract, study in mice suggests

Pilot Study: Measuring Relaxation Response to the iLs Dreampad

Researchers are on their way to predicting what side effects you'll experience from a drug

Print Page
Email Article

Evidence of Green Tea’s Promise ‘Continues to Brew’ - M. D. Anderson Cancer Center Reports on Controlled Trial

  [ 110 votes ]   [ Discuss This Article ] • November 5, 2009

Although scientists are reluctant to endorse green tea as a cancer prevention method, evidence continues to grow regarding the chemically complex drink’s potential benefits - including results of a new randomized, controlled trial by researchers at University of Texas M. D. Anderson Cancer Center, which suggest it had some inhibiting effect in patients with a pre-malignant condition known as oral leukoplakia.

As reported in a report published online Nov 5 by Cancer Prevention Research(1), a team headed by Vassiliki Papadimitrakopoulo, MD, professor of medicine in M.D. Anderson’s Department of Thoracic/Head and Neck Medical Oncology, tested green tea extract taken orally for three months by 41 patients diagnosed with oral leukoplakia and therefore at high risk of developing oral cancer.

The patients were divided into cohorts taking either placebo or one of three different doses of green tea extract 500 mg/m2, 750 mg/m2 or 1,000 mg/m2 [mg/m2 refers to milligrams per meter squared of body mass – calculated by a formula using height and weight to reflect a person’s relative size].

The researchers assessed clinical response in oral pre-malignant lesions and found:

• 58.8% of patients at the highest doses displayed clinical response,

• Compared with 18.2% among those taking placebo.

They also observed:

• A trend toward improved histology [cell & tissue integrity],

• And a trend towards improvement in a handful of biomarkers that may be important in predicting cancer development.

Patients were followed for 27.5 months and at the end of the study period, 15 developed oral cancer.

• Although there was no difference in oral cancer development overall between those who took green tea and those who did not,

• Patients who presented with mild to moderate dysplasia [abnormal cell growth] had a longer time to develop oral cancer if they took green tea extract.

Although encouraged by the results, Dr. Papadimitrakopoulo cautioned against any recommendations that green tea could definitely prevent cancer.

“This is a phase II study with a very limited number of patients who took what would be the equivalent of drinking eight to 10 cups of green tea every single day,” she said. “We cannot with certainty claim prevention benefits from a trial this size.”

Dong Shin, MD, (professor of hematology and medical oncology at Emory School of Medicine, and a Cancer Prevention Research editorial board member) agreed, but said this trial is certainly a step in the right direction. “A clinical trial with a natural compound is no easy task, and these researchers have accomplished that,” Dr. Shin stated in a companion article commenting on the trial(2). “The lack of toxicity is also important because often when you give supplements at higher doses than what would occur naturally, you induce nausea and vomiting. That did not happen in this trial.”

Neither researcher had a reason why patients concerned about cancer should not drink green tea, but they cautioned against relying on the beverage to definitively reduce their risk of cancer.

“The goal of this kind of research is to determine whether or not these supplements have long-term prevention effects," said Dr. Papadimitrakopoulou. "More research - including studies in which individuals at high risk are exposed to these supplements for longer time period - is still needed to answer that sort of question.”
Cited Articles:
1. “Phase II Randomized, Placebo-Controlled Trial of Green Tea Extract in Patients with High-Risk Oral Premalignant Lesions”
2. “Oral Cancer Prevention Advances with a Translational Trial of Green Tea”

• American Association for Cancer Research (which publishes Cancer Prevention Research) news release Nov 5, 2009
• University of Texas M. D. Anderson Cancer Center news release Nov 5, 2009

Note: This information has not been evaluated by the FDA. It is general and is not meant to prevent, diagnose, treat or cure any illness, condition, or disease. It is very important that you make no change in your healthcare plan or health support regimen without researching and discussing it in collaboration with your professional healthcare team.

Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra ATP+, Double Strength FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing