ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

Artificial sweeteners linked to risk of weight gain, heart disease and other health issues

All About Ginkgo Biloba: Benefits of This Timeless Herbal Supplement

Yarrow Oil: Here's Why It Deserves a Place in Your First-Aid Kit

Vitamin D supplement use associated with lower risk of breast cancer

Carnitine deficiency suggested as contributor to autism

Lutein — An Important Nutrient for Eye and Brain Health

Hop Oil: A Safe Sleep Aide

White Camphor Oil: The Purest Camphor Oil

Taurine: Facts About This Crucial Amino Acid

 
Print Page
Email Article

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV – Source: Virology, Jan 26, 2010

  [ 6 votes ]   [ Discuss This Article ]
By Kristin Stieler, Nicole Fischer, et al. • www.ProHealth.com • February 1, 2010


Recently, the first human infection with an exogenous gammaretrovirus (XMRV) was reported.

In its initial description, XMRV was confined to prostate stromal fibroblasts [cells in connective tissue], although subsequent reports demonstrated XMRV protein expression in prostate epithelial cells [in the organ’s lining].

Most recently, XMRV has been detected in blood cells of patients with chronic fatigue syndrome.

The aim of this study was to elucidate the transmission routes and tissue tropism [tissue that supports the growth] of XMRV by comparing its host range, receptor usage and LTR functionality with other MLV isolates. [the LTR or “long terminal repeat” of a retrovirus “is the control center for gene expression.” MLV is amphotropic murine leukemia virus.]

• We demonstrate using pseudotype experiments that XMRV Env mediates efficient infection of cells from different species.

• We show that replication competent XMRV infects various human cell types, including hematopoietic cell lines and prostate stromal fibroblasts. [Hematopoietic stem calls, found in the bone marrow, give rise to all the blood cell types.]

• XMRV-LTR activity is significantly higher in the prostate cancer cell line LNCaP and in prostate stromal fibroblasts, compared to other cell types tested and could be one factor contributing to efficient viral spread in prostate tissue.

Source: Virology, Jan 26, 2010. PMID: 20110097, by Stieler K, Schulz C, Lavanya M, Aepfelbacher M, Stocking C, Fischer N. Institute for Medical Microbiology and Virology, University Medical Center Eppendorf, Hamburg, Germany; Heinrich-Pette-Institute, Hamburg, Germany; Institut de Genetique Moleculaire de Montpellier, Montpellier, France. [E-mail: nfischer@uke.de]





Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients
"It's Not Easy Being Green" - But It Is Healthy
How One Tiny Molecule Turned into One Huge Health Breakthrough How One Tiny Molecule Turned into One Huge Health Breakthrough

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map