ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Natural Remedies for the Prevention of Dry Eyes

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

What Makes Spanish Marjoram Oil Special?

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

8 Chia Seed Recipes

 
Print Page
Email Article

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV – Source: Virology, Jan 26, 2010

  [ 6 votes ]   [ Discuss This Article ]
By Kristin Stieler, Nicole Fischer, et al. • www.ProHealth.com • February 1, 2010


Recently, the first human infection with an exogenous gammaretrovirus (XMRV) was reported.

In its initial description, XMRV was confined to prostate stromal fibroblasts [cells in connective tissue], although subsequent reports demonstrated XMRV protein expression in prostate epithelial cells [in the organ’s lining].

Most recently, XMRV has been detected in blood cells of patients with chronic fatigue syndrome.

The aim of this study was to elucidate the transmission routes and tissue tropism [tissue that supports the growth] of XMRV by comparing its host range, receptor usage and LTR functionality with other MLV isolates. [the LTR or “long terminal repeat” of a retrovirus “is the control center for gene expression.” MLV is amphotropic murine leukemia virus.]

• We demonstrate using pseudotype experiments that XMRV Env mediates efficient infection of cells from different species.

• We show that replication competent XMRV infects various human cell types, including hematopoietic cell lines and prostate stromal fibroblasts. [Hematopoietic stem calls, found in the bone marrow, give rise to all the blood cell types.]

• XMRV-LTR activity is significantly higher in the prostate cancer cell line LNCaP and in prostate stromal fibroblasts, compared to other cell types tested and could be one factor contributing to efficient viral spread in prostate tissue.

Source: Virology, Jan 26, 2010. PMID: 20110097, by Stieler K, Schulz C, Lavanya M, Aepfelbacher M, Stocking C, Fischer N. Institute for Medical Microbiology and Virology, University Medical Center Eppendorf, Hamburg, Germany; Heinrich-Pette-Institute, Hamburg, Germany; Institut de Genetique Moleculaire de Montpellier, Montpellier, France. [E-mail: nfischer@uke.de]





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Vitamin D3 Extreme™ Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health
Vital Molecule Increases Cellular Energy and Improves Cognitive Function Vital Molecule Increases Cellular Energy and Improves Cognitive Function
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map