ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Astaxanthin Is a Longevity Promoter

Meta-analysis links vitamin D deficiency with increased risk of mortality during 10.5 year median pe...

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Valerian Root Help You Sleep Better?

Eight servings of veggies a day is clearly best for the heart

The Many Wonders of Calming Sandalwood Oil

Can Ginkgo Give Your Brain a Boost?

Fighting Statin-Induced Diabetes with CoQ10

 
Print Page
Email Article

Genoprotective effects of green tea (Camellia sinensis) in human subjects: Results of a controlled supplementation trial – Source: British Journal of Nutrition, Sep 2010

  [ 5 votes ]   [ Discuss This Article ]
By KC Han, WC Wong, Iris FF Benzie • www.ProHealth.com • September 13, 2010


Green tea is rich in polyphenolic antioxidants and has widely reported but largely unsubstantiated health benefits. In the present study, genoprotective effects of two types of green tea were studied both in an in vitro [lab] and in a human supplementation trial.

• For the in vitro study, human lymphocytes were pre-incubated in tea (0.005-0.1 %, w/v), washed and subjected to oxidant challenge induced by H2O2.

• In a placebo-controlled, cross-over supplementation study, eighteen healthy volunteers took 2 x 150 ml/d of 1% (w/v) green tea ('Longjing' green tea or 'screw-shaped' green tea) or water (control) for 4 weeks (n 6).

Subjects took all the three treatments in a random order, with 6 weeks' washout between each treatment. Fasting blood and urine were collected before and after each treatment. The comet assay was used to measure the resistance of lymphocytic DNA to H2O2-induced challenge. Basal oxidation-induced DNA damage was measured using the formamidopyrimidine glycosylase (Fpg) enzyme-assisted comet assay. Urine 7,8-dihydro-2-deoxyguanosine (8-oxodG, mol/mmol creatinine), a biomarker of whole-body oxidative stress, was measured by liquid chromatography with tandem MS.

• In vitro testing results of tea-treated cells showed increased (P < 0.05) resistance of DNA to the challenge.

• In the supplementation trial, a significant (P < 0.05) increase in resistance was also observed.

• Furthermore, the FPg comet data showed more than 20% decrease in DNA damage with tea supplementation: mean and standard deviation changes in %DNA in comet tail in the Fpg-assisted comet assay were: - 5.96 (sd 3.83) % after Longjing tea; - 6.22 (sd 3.34) % after screw-shaped tea; +0.91 (sd 5.79) % after water (P < 0.05). No significant changes in urine 8-oxodG were seen.

The results indicate that green tea has significant genoprotective effects and provide evidence for green tea as a 'functional food'.

Source: British Journal of Nutrition, Sep 2010. PMID: 20807462, by Han KC, Wong WC, Benzie IF. Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong. [Email: iris.benzie@inet.polyu.edu.hk]





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

How Glutathione Can Save Your Life How Glutathione Can Save Your Life
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map