ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The Health Benefits of Manuka Honey

Increase Your Magnesium Intake

Vitamin D supplementation could ease IBS symptoms

Top Tips to Boost Your Immunity

11 Amazing Health Benefits of Using Baking Soda

Nicotinamide riboside shows promise for treatment of Alzheimer’s disease

Exercise, calcium, vitamin D, and other factors linked with fewer injurious falls

Vitamin D3 Is a Powerhouse for Your Heart

Curcumin Supplementation May Impart Long-Term Cognitive Benefits

Rhodiola — A Powerful Adaptogen That Boosts Vitality and Performance, Eases Depression and Combats B...

 
Print Page
Email Article

Drug safely retards MS progression for many in two-year, 24-country Phase III trial

  [ 2 votes ]   [ 1 Comment ]
www.ProHealth.com • April 28, 2011


“These exciting results confirm that laquinimod has a significant impact on progression of disability and disease activity, while maintaining a high safety profile.”

The orally-administered drug laquinimod reduced the number of relapses for people with multiple sclerosis (MS), in a large, long-term Phase III clinical study presented as breaking news at the annual meeting of the American Academy of Neurology in April.

The study involved 1,106 people with relapsing-remitting MS* in 24 countries. The participants received either a once-daily oral dose of 0.6 mg laquinimod or a matching placebo for two years. Eighty percent of those taking laquinimod and 77% of those taking the placebo finished the two-year study.

• Patients treated with laquinimod experienced a statistically significant [average] reduction of 23% in annual relapse rate, compared to patients treated with a placebo.

• Additionally, there was a [average] reduction of 36% in disability progression, as well as a 33% reduction in brain atrophy for those people treated with laquinimod.

“These exciting results confirm that laquinimod has a significant impact on progression of disability and disease activity, while maintaining a high safety profile,” said lead author Giancarlo Comi, MD, director of the Department of Neurology and Institute of Experimental Neurology at the Scientific Institute and University Vita-Salute San Raffaele in Milan, Italy.

“This may be attributed to the novel mechanism of action of laquinimod, which effectively and safely addressed both the acute inflammatory activity and the accumulation of irreversible tissue damage,” Dr. Comi adds. “This suggests a substantial future role for laquinimod in the treatment of MS.”

Laquinimod was safe and well tolerated. Overall frequencies of adverse events were low and comparable to those observed in the placebo group.

“The incidence of liver enzyme elevation was higher in laquinimod treated patients,” said Comi. “However, these elevations were temporary, reversible and did not lead to any signs of liver problems.”

[Note: Laquinimod's mechanism of action in treatment of MS is not fully understood, but studies suggest it modulates immune system response from pro-inflammatory to anti-inflammatory by preventing the immune T cells which cause nerve damage in MS from crossing the blood brain barrier & entering the central nervous system. For more, see www.emsp.org.]

* See video briefly describing this and other forms of MS at the American Academy of Neurology website.

Source: American Academy of Neurology, Apr 11, 2011




Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor®


Article Comments Post a Comment

Drug for MS
Posted by: victoria
Apr 29, 2011
It's too bad they won't fund studies of Low Dose Naltrexone / LDN
Reply Reply
 
Optimized Curcumin Longvida with Omega-3

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Breakthrough Form of Magnesium Enhances Memory and Cognitive Function Breakthrough Form of Magnesium Enhances Memory and Cognitive Function
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
The New Dual Activation Pain Relief Cream The New Dual Activation Pain Relief Cream
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Vitamin E: Super Antioxidant We Only Thought We Knew Vitamin E: Super Antioxidant We Only Thought We Knew

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map