Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

How Good Fats Prevent Heart Disease

Anti-inflammatory "No More Aches and Pains" Smoothie Bowl

The Bees' Best-Kept Secret: The Amazing Health Benefits of Propolis

Acupuncture: Why It Works

For women, healthy diets may help with mobility when aging

The Relationship Between Vitamin D and Insulin Resistance

8 Things to Consider for Depression

ACTION ALERT: Improve US chronic pain care

VIDEO: Living with Chronic Pain

Supplements Proven Beneficial for Depression

 
Print Page
Email Article

Cod liver oil (omega-3 fatty acids) as an non-steroidal anti-inflammatory drug sparing agent in rheumatoid arthritis – Source: Rheumatology, May 2008

  [ 1 vote ]   [ Discuss This Article ]
By B Galarraga, JJ Belch, et al. • www.ProHealth.com • April 29, 2008


[Note: The full text of this open-access article is available free online at http://rheumatology.oxfordjournals.org/cgi/reprint/47/5/665]

Objectives: Dose-dependant gastrointestinal and cardiovascular side-effects limit the use of NSAIDs [non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen, and indomethacin] in the management of RA [rheumatoid arthritis – a chronic autoimmune inflammatory joint disease in which inflammation plays a key role]. The n-3 [omega-3] essential fatty acids (EFAs) have previously demonstrated some anti-inflammatory and NSAID-sparing properties. The objective of this study was to determine whether cod liver oil supplementation helps reduce daily NSAID requirement of patients with RA.

Methods: Dual-centre, double-blind placebo-controlled randomized study of 9 months' duration. Ninety-seven patients with RA were randomized to take either 10 g of cod liver oil containing 2.2 g of n-3 EFAs or air-filled identical placebo capsules. Documentation of NSAID daily requirement, clinical and laboratory parameters of RA disease activity and safety checks were done at 0, 4, 12, 24 and 36 weeks.

At 12 weeks, patients were instructed to gradually reduce, and if possible, stop their NSAID intake. Relative reduction of daily NSAID requirement by >30% after 9 months was the primary outcome measure.

Results: Fifty-eight patients (60%) completed the study. Out of 49 patients, 19 (39%) in the cod liver oil group; and out of 48 patients, 5 (10%) in the placebo group were able to reduce their daily NSAID requirement by >30% (P = 0.002, chi-squared test).

No differences between the groups were observed in the clinical parameters of RA disease activity or in the side-effects observed.

Conclusions: This study suggests that cod liver oil supplements containing omega-3 fatty acids can be used as NSAID-sparing agents in RA patients.

Source: Rheumatology (Oxford), May 2008;47(5):665-9. PMID: 18362100, by Galarraga B, Ho M, Youssef HM, Hill A, McMahon H, Hall C, Ogston S, Nuki G, Belch JJ. Vascular and Inflammatory Diseases Research Unit, University Division of Medicine and Therapeutics, Ninewells Hospital and Medical School, Dundee, UK. [E-mail: b.galarraga@dundee.ac.uk]





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor® FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Complete and Natural Menopause Relief Complete and Natural Menopause Relief
How Glutathione Can Save Your Life How Glutathione Can Save Your Life
How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map