ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

How One Tiny Molecule Turned into One Huge Health Breakthrough

Nutrients Boost Stem Cell Function

Humans have three times more brown body fat

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

How B Vitamins Improve Brain Health, Cognition, Psychiatric Problems and Mood Disorders

Dietary prebiotics improve sleep, buffer impacts of stress, says study

Exercises to Help Prevent Urinary Incontinence

Higher red blood cell omega 3 levels in women linked to lower risk of mortality over 14.9 year media...

 
Print Page
Email Article

Medication dosing patterns associated with duloxetine and pregabalin among patients with fibromyalgia – Source: Current Medical Research and Opinion, Aug 3, 2011

  [ 2 votes ]   [ 1 Comment ]
By P Sun, et al. • www.ProHealth.com • August 4, 2011


Objective: To examine medication dosing patterns of duloxetine [Cymbalta] and pregabalin [Lyrica] among patients with fibromyalgia.

Methods: From a large US administrative claims database, commercially insured fibromyalgia patients aged 18-64 who initiated duloxetine or pregabalin in 2006 were selected.

Initiation was defined as a 90-day medication gap, with the dispense date of the first initiation as the index date.

All patients selected had continuous enrollment over the 12-month pre- and post-index periods, and were classified into the duloxetine or pregabalin cohorts based on their index agent.

Initial daily dose, average daily dose over the 12-month post-index period, mean and median daily doses, and daily costs of each of the first 12 prescriptions were examined for both the duloxetine and pregabalin cohorts.

Results: Both the duloxetine (n = 3,773) and pregabalin (n = 4,189) cohorts had a mean age of 50 years (median age: 52 vs. 53).

The average initial daily dose was 55.7mg for duloxetine and 161.5mg for pregabalin. Over the 12-month post-index period, the average daily dose per patient was 55.6mg for duloxetine and 195.7mg for pregabalin.

The average daily doses for the first 12 duloxetine prescriptions ranged from 55.7mg to 60.3mg, with the mean daily costs between $3.77 and $4.59. For the first 12 pregabalin prescriptions, the average daily dose increased from 161.5mg to 282.4mg, while the average daily costs ranged between $4.30 and $4.61.

Conclusions:
Among patients with fibromyalgia, duloxetine and pregabalin initiators had different dosing patterns.

The average daily dose for duloxetine [Cymbalta] was relatively stable over time, while pregabalin [Lyrica] patients had significant dose increase over the 12-month post-index period.

Source: Current Medical Research and Opinion, Aug 3, 2011. PMID: 21810060, by Sun P, Zhao Y, Zhao Z, Watson P. Kailo Research Group , Indianapolis, Indiana, USA.





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Vitamin D3 Extreme™ Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

This matches with my experience
Posted by: Scribelle
Aug 25, 2011
I have been on both Lyrica and Cymbalta. It has been my experience that my Cymbalta dose has remained the same. However, the Lyrica was increased, and finally seemed to stop working. I was then removed from Lyrica and put on generic neurontin. The relief was immediate. This makes me wonder if it is possible to develop a tolerance to Lyrica.
Reply Reply
 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7
Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
Fighting Fatigue with Ground-breaking French Oak Wood Extract Fighting Fatigue with Ground-breaking French Oak Wood Extract

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map