ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|
 
Print Page
Email Article

Effects of Exercise on Serotonin in Fibromyalgia

  [ 9 votes ]   [ 3 Comments ]
www.ProHealth.com • February 5, 2014

previous article next article

Note: You may read the full text of this article free HERE.

Effects of physical exercise on serum levels of serotonin and its metabolite in fibromyalgia: a randomized pilot study.

By Valéria Valim, et al.

Abstract:

To evaluate the effects of aerobic training and stretching on serum levels of serotonin (5HT) and its main metabolite 5-hydroxindolacetic acid (5HIAA).

Twenty-two women with FM were randomized into one of two exercise modalities (aerobic walking exercise or stretching exercise) to be accomplished three times a week for 20 weeks. The serum levels of 5HT and 5HIAA were evaluated before and after the exercise program by high performance liquid chromatography (HPLC) with colorimetric detection.
  • Within group analysis (pre-post) showed that serum levels of both 5HT and 5HIAA changed significantly in the aerobic group during the 20-week course of therapy (5HT: P = 0,03; 5HIAA: P = 0,003).

  • In the stretching group, however, no statistically significant change was observed (5HT: P=0,491; 5HIAA: P=0,549).

  • Between group statistical comparisons of laboratory measures disclosed that aerobic training was superior to stretching in that it significantly increased the levels of 5HIAA (F test = 6.61; P = 0.01), but the average difference between groups on the levels of 5HT did not meet significance criteria (F test = 3.42; P = 0.08).

Aerobic training increases the 5HIAA and 5HT levels and it could explain why aerobic exercise can improve symptoms in fibromyalgia syndrome patient more than stretching exercise.

Source: Revista Brasileira de Reumatologia, December 2013. By Valéria Valim, Jamil Natour, Yangming Xiao, Abraão Ferraz Alves Pereira, Beatriz Baptista da Cunha Lopes, Daniel Feldman Pollak, Eliana Zandonade and Irwin Jon Russell.


previous article
  Rating 2.9 (9 votes) next article




DISCUSS THIS ARTICLE   (3 existing comments) Post a Comment 


here we go again
Posted by: roge
Feb 6, 2014
exercise will make your fm better. im sorry but i am so tired of these studies, it is 2014 and not the 1980s with the ol exercise and take elavil and you will be better,cmon researchers can we please try and find the main pathology here so we can better treat this terrible disease.
Reply Reply

 
walk
Posted by: roge
Feb 6, 2014
this from a 43 yr old male athlete who can bow barely walk now due to chronic plantar facitis and achilles tendonitis and around 15 other tendon issues - those who say FM is just a central sensitization are so wrong, there is definitely a peripheral aspect with dysfunctionl muscles/facia and tendons. It is neuromuscular and immune system is involved as well.

 


The value of this study
Posted by: IanH
Feb 6, 2014
is that it does show that some FM sufferers are no different from everyone else is response to aerobic exercise in regard to 5-HT and its metabolite. The increase in 5HT may be helpful but the study needs to go further and look at whether the immune variables and neurokinins (such as substance P) are influenced. There is nothing in the study to verify that the pain related variables are affected.

The other thing is that if these 22 women could successfully complete the aerobic walking exercises then I suggest that their FM was moderate or mild and they did not have ME. This means they are a subset of FM patients. How were they selected?

Always remember : these "illnesses" are heterogeneous and diagnosis (selection) is still a problem.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products
Natural Resveratrol Natural Resveratrol
Powerful Antioxidant Support + Positive Anti-aging Effects
Vitamin D3 5000 IU Vitamin D3 5000 IU
Give your body a boost with the sunshine vitamin
Omega 3-6-9 Omega 3-6-9
All three EFAs in one convenient form
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
OsteoTec™ UC-II® OsteoTec™ UC-II®
A True Breakthrough in Joint health

Most Viewed Articles
What's the Hidden Cause Behind YOUR Fibromyalgia Flares? [more]

Pridgen Reports Fibromyalgia Antiviral Trial Results “Very Positive”: Predicts New Approach Will Be ... [more]

Massage Therapy Studies for Fibromyalgia Reviewed [more]

How to Limit or Minimize Your Fibromyalgia Flare [more]

Breaking News: FDA’s Sneak Attempt to Ban Another B Vitamin [more]

Mitochondrial Dysfunction, Post-Exertional Malaise and CFS/ME [more]

The Devil Is In The Details – A Herpes Simplex Virus Inquiry For Fibromyalgia and Chronic Fatigue Sy... [more]

FDA Says Sponsors of Chronic Fatigue Syndrome Drugs can Rely on Patient-Reported Outcomes [more]

Sensory Overload: Sources and Strategies [more]

Sympathetic Nervous System Dysfunction in FIbromyalgia and Overlapping Conditions [more]


FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing