ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Lilac Oil: More Than Just for Fragrance

Eat More Yogurt and Avoid Osteoporosis

Safflower: An Economically Important Herb That Can Benefit Humans and Animals Alike

What Is Bilberry Good For?

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Resveratrol Improves Arteries

New research adds evidence to association between omega 3 levels and brain maintenance

 
Print Page
Email Article

Birth control pills associated with breast cancer risk in BRCA1 mutation carriers

  [ 18 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 4, 2002


Women who carry mutations in the BRCA1 breast cancer susceptibility gene and have a history of oral contraceptive use may have an increased risk of early-onset breast cancer, according to a large-scale study in the December 4 issue of the Journal of the National Cancer Institute.

Women with BRCA1 and BRCA2 mutations have a 50% to 80% lifetime risk of developing breast cancer. This risk may be modified by factors that influence the level of hormones produced by the body. Whether this risk is modified by exogenous hormones, such as oral contraceptives or hormone replacement therapy, is unknown. Long-term oral contraceptive use has been associated with a modest increase in the risk of breast cancer in the general population and a decrease in the risk of ovarian cancer.

To examine whether the use of oral contraceptives is associated with the risk of hereditary breast cancer, Steven A. Narod, M.D., of the Sunnybrook and Women's College Health Sciences Centre and the University of Toronto, and his colleagues looked at history of oral contraceptive use among 1,311 women with BRCA1 or BRCA2 mutations who had breast cancer and 1,311 mutation carriers without breast cancer. The women were recruited from 52 centers in 11 countries.

Among women with BRCA1 mutations, those who used oral contraceptives for 5 or more years had a 33% increase in the risk of breast cancer, compared with women who had never used oral contraceptives. The risk was also elevated in women who used contraceptives before age 30, women who were diagnosed with breast cancer before age 40, and women who first used oral contraceptives before 1975. In contrast, Narod and his colleagues did not find any increase in breast cancer risk in BRCA2 mutation carriers, but they say that more studies should be done to confirm these findings.

The authors say that for women carrying a BRCA1 mutation, age should be an important consideration when prescribing an oral contraceptive. The new findings suggest that "oral contraceptive use after age 30 is not likely to increase the risk of breast cancer among BRCA1 mutation carriers and can be used safely to reduce the risk of ovarian cancer," they conclude.



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map