ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

A Little Zinc Goes a Long Way

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

More evidence for calorie restriction’s longevity effect

Vitamin D deficiency increases risk of chronic headache

Wearable biosensors can flag illness, Lyme disease, risk for diabetes; low airplane oxygen

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Iron (And More) For Lasting, Natural Energy

Affordable Care Act made cancer screening more accessible for millions, study finds

Metabolic syndrome increases the need for vitamin E

 
Print Page
Email Article

Novel Disease Mechanism Underlying Rheumatoid Arthritis

  [ 112 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 30, 2004


Posted By: News-Medical in Medical Research News

Investigators at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) have identified a novel disease mechanism underlying rheumatoid arthritis that may open the door to new therapies for this and other debilitating autoimmune disorders. In an article appearing in the September 1 issue of the Journal of Immunology, principal investigator Terry J. Smith, MD describes research that identifies an interaction between antibodies found in patients with rheumatoid arthritis and the insulin-like growth factor receptor (IGF-1R) as a cause of inflammation and lymphocyte infiltration.

Dr.Smith published similar results last year dealing with Graves' disease, an autoimmune disorder affecting the thyroid gland and eyes. Dr. Smith and his colleagues found that specific immunoglobins "turn on" the IGF-1R much like IGF-1 itself is known to do. Once the receptor is "on", a number of molecular events occur, including the production of two very powerful factors known to trigger T lymphocytes and direct them to sites of inflammation. In addition, the researchers found that blocking the interaction between the antibodies and IGF-1R arrests the progression of molecular events leading to T cell activation.

According to Dr. Smith, "It is possible that these findings will allow us for the first time to interrupt the disease process before any lasting damage occurs." Rheumatoid arthritis is one of several autoimmune disorders in which cellular defense mechanisms identify the body's own tissues as foreign and seek to destroy them. Other autoimmune disorders include such ailments as Graves' disease, multiple sclerosis and lupus. This research suggests that there could be a common therapeutic strategy for these conditions.

According to Kenneth P. Trevett, JD, President and CEO of LA BioMed, "The research by Dr. Smith offers the promise of a magic bullet treatment for several autoimmune diseases." http://www.rei.edu/



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Breaking Through the Mental Fog Breaking Through the Mental Fog

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map