ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

Artificial sweeteners linked to risk of weight gain, heart disease and other health issues

All About Ginkgo Biloba: Benefits of This Timeless Herbal Supplement

Yarrow Oil: Here's Why It Deserves a Place in Your First-Aid Kit

Vitamin D supplement use associated with lower risk of breast cancer

Carnitine deficiency suggested as contributor to autism

Hop Oil: A Safe Sleep Aide

Lutein — An Important Nutrient for Eye and Brain Health

White Camphor Oil: The Purest Camphor Oil

Taurine: Facts About This Crucial Amino Acid

 
Print Page
Email Article

New Heart Muscle Cells Produced From Bone Marrow

  [ 53 votes ]   [ Discuss This Article ]
www.ProHealth.com • March 12, 2003


Mayo Clinic researchers have proven for the first time that cells produced by the bone marrow can form new heart-muscle cells in adults, providing an important boost to research that could enable the body to replace heart muscle damaged by heart attack. The findings are published in Circulation: Journal of the American Heart Association.

"Until recently, the heart has been seen as an organ that cannot be healed," says Noel Caplice, M.D., the Mayo Clinic cardiologist who led the study. "Heart-attack damage to the myocardium, or heart muscle, was considered irreversible. This study points the way to a process that could lead to heart repair."

The researchers studied four female patients with leukemia who had survived 35 to 600 days after receiving bone-marrow transplants from male donors. Heart tissue samples were examined at autopsy using special staining techniques, which showed that a small portion of the heart-muscle cells, or cardiomyocytes, contained male genetic material and had therefore originated from the donor marrow. Of the more than 80,000 cell nuclei examined, about 1 in 425 (.23 percent) contained the y chromosome.

The study is important because it is the first confirmation that progenitor cells from outside the heart are capable of forming new heart muscle cells. "These progenitor cells are produced by the bone marrow and circulate in the blood," explains Dr. Caplice. "They are like stem cells in that they have potential to develop into various kinds of cells. Given the right biological signals, we have now shown they can become heart cells."

Dr. Caplice says the study has significant implications for future research. "Under normal conditions, with less than one percent of heart-muscle cells originating from these progenitor cells, they obviously are not adding much to the heart's pumping strength. But if we can determine the signaling mechanism that causes progenitor cells to develop into cardiomyocytes, we may be able to boost the response and induce more of them to proceed in that direction. A growth hormone delivered to the heart could perhaps lead to formation of new muscle around an area of scar tissue, so the heart could actually be healed after being damaged by heart attack. This study provides an important validation of the potential for this new line of research," Dr. Caplice concludes.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Ultra EPA  - Fish Oil


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
Break Free From Fibromyalgia Break Free From Fibromyalgia
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map