ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

How One Tiny Molecule Turned into One Huge Health Breakthrough

Nutrients Boost Stem Cell Function

Humans have three times more brown body fat

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

How B Vitamins Improve Brain Health, Cognition, Psychiatric Problems and Mood Disorders

Dietary prebiotics improve sleep, buffer impacts of stress, says study

Exercises to Help Prevent Urinary Incontinence

Higher red blood cell omega 3 levels in women linked to lower risk of mortality over 14.9 year media...

 
Print Page
Email Article

Studies Show that AD Brain Changes Occur Before Clinical Diagnosis

  [ Not Yet Rated ]   [ Discuss This Article ]
By 1999 Progress Report by the NIA/NIH • www.ProHealth.com • December 13, 1999


Several recent studies funded by NIA have attempted to explore the cause and development of Alzheimer's through examinations of the brains of individuals who have died, both those with Alzheimer's and those without. These studies allow researchers to track the changes in the brain that occur as Alzheimer's develops and to understand the damage that happens early, before clinical signs of AD appear. For example, scientists at the Washington University School of Medicine in St. Louis studied the distribution and density of tangles and plaques in 62 clinically followed cases, some of whom had mild dementia, some of whom had severe dementia at death, and some of whom were healthy at death (Price and Morris, 1999). They found that some of the healthy brains had either amyloid plaques or neurofibrillary tangles, suggesting that initial formation of tangles and plaques in healthy aging may be independent of each other. However, some of the brains of those who had been diagnosed with mild dementia had widely distributed plaques and a substantial increase in the number of tangles relative to the healthy brains. The study authors suggest that amyloid deposition somehow increases the rate at which tangles are formed as "preclinical" Alzheimer's disease progresses into clinically diagnosed dementia.

In another study looking at changes in neurofibrillary tangles in the brains of deceased elderly men and women who, during their lives, had no dementia, questionable dementia, mild dementia, and moderate dementia, a team of investigators at the Mount Sinai School of Medicine and Bronx Veterans Affairs Medical Center found that tangles were present in the entorhinal cortex and hippocampus of all the subjects (Haroutunian et al., 1999). As dementia became more severe however, the tangles appeared in additional regions of the brain and became more dense. These studies reinforce the idea that changes characteristic of those seen in the AD brain can begin in individuals well before any clinical diagnosis is made.

Source:
National Institutes of Health
National Institute on Aging
1999 PROGRESS REPORT ON ALZHEIMER'S DISEASE



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra ATP+, Double Strength Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia
Breakthrough Form of Magnesium Enhances Memory and Cognitive Function Breakthrough Form of Magnesium Enhances Memory and Cognitive Function
The New Dual Activation Pain Relief Cream The New Dual Activation Pain Relief Cream

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map