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The role of essential fatty acids in Chronic Fatigue Syndrome (CFS). A case- controlled study of red-cell memebrane essential fatty acids (EFA) & a placebo-controlled study

  [ 60 votes ]   [ Discuss This Article ]
www.ProHealth.com • February 4, 1999


OBJECTIVE: To replicate the treatment study by Behan et al.
(1990) using current research criteria for Chronic Fatigue
Syndrome (CFS).

METHOD: Fifty patients who fulfilled the
Oxford Criteria for CFS were randomly allocated to treatment
with either Efamol Marine or placebo for 3 months. They were
seen monthly and completed a physical symptoms checklist and
the Beck Inventory for Depression and reported if they were
the same, better or worse at the end of the study.

RESULTS:
Symptoms generally improved with time but not significantly
and there were no significant differences between the
treatment and placebo groups. Pretreatment red-cell membrane
(RBC) lipids of patients compared with age-and sex-matched
normal controls showed no significant differences.

DISCUSSION:
The results of this study contrast sharply with the previous
study where 85% of patients had a clinically significant
improvement of symptoms with Efamol Marine over a 3-month
treatment period.

Warren G, McKendrick M, Peet M




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