ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Scientifically-designed fasting diet lowers risks for major diseases

Is Magnesium the Missing Link in Your Heart Healthy Routine?

More evidence for calorie restriction’s longevity effect

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

A Little Zinc Goes a Long Way

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Get the Most From Your Green Tea

Iron (And More) For Lasting, Natural Energy

Metabolic syndrome increases the need for vitamin E

 
Print Page
Email Article

Scientists Discover Brain Changes in Young Adults at Genetic Risk for Alzheimer's

  [ 129 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 16, 2002


Decades before symptoms appear, scientists can detect abnormalities in the brains of healthy adults in their 20s and 30s who are at genetic risk for developing Alzheimer's disease, according to Eric Reiman, M.D., Scientific Director of the PET Center at Good Samaritan Regional Medical Center in Phoenix, Ariz. at the 8th International Conference on Alzheimer's Disease and Related Disorders.

Using a brain-imaging technique called positron emission tomography (PET), scientists were able to study young adults carrying the gene called apolipoprotein E, (ApoE), one of three common forms of a gene that codes production of a cholesterol carrying protein. The ApoE gene occurs in about one-fourth of the population, and individuals with ApoE have an increased risk - although not a certainty - of developing late-onset Alzheimer's disease. Late-onset Alzheimer's disease is the most common form of Alzheimer's, in which memory and thinking problems begin after the age of 60.

In the study, a dozen healthy young adults who carry ApoE were compared to 15 young adults who do not carry the gene. Clinical ratings and neuropsychological tests to assess the participants' memory and thinking, with PET imaging and powerful brain mapping software were used to map differences in brain activity between the ApoE carriers and noncarriers.

Although the young adults carrying the ApoE gene performed normally on the memory and thinking tests, Reiman and colleagues found that they had abnormally low brain activity in the same regions of the brain as patients with the clinical diagnosis of Alzheimer's disease.

"Young adults at risk of Alzheimer's disease have detectable brain abnormalities several decades before the possible onset of memory and thinking problems," said Reiman, who also serves as professor of psychiatry at the University of Arizona and director of the Arizona Alzheimer's Research Center. "Our findings underscore the possibility of finding treatments to prevent Alzheimer's disease at the earliest possible time and in the most effective way, and they reinforce the possibility of using PET to help establish the effectiveness of these prevention therapies without having to wait many years to determine whether or when treated individuals develop symptoms. Meanwhile, it is important to recognize that PET imaging technology should not be used to predict a person's risk for developing this terrible disorder."

Based on previous research, it is believed that the low brain activity found in patients clinically affected by Alzheimer's disease, and in cognitively normal people at genetic risk for the disorder, progress as the person ages. Studies led by Reiman and previously published in the New England Journal of Medicine and the Proceedings of the National Academy of Sciences found that 50- to 65-year-old carriers of the Apo£ gene had abnormally low brain activity in the same brain regions as clinically affected patients,. They also reported that this activity continues to decline over time, and that PET could efficiently test the potential of treatments to prevent Alzheimer's disease.

"I think it is very important to emphasize that APOE-£ is only one of many risks for Alzheimer's disease. Researchers have estimated there are a number of additional genes (not yet identified) that will both increase and decrease risk," explains Marilyn Albert, Ph.D., Professor of Psychiatry and Neurology, Harvard Medical School. "It is also clear there are environmental risk factors that influence the development of Alzheimer's disease. It is important to understand the impact of these risks on the brain so that we can understand how best to reduce risk for AD, and develop better treatments, and this study is part of that effort."



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map