Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

Greater intake of dietary omega-3 fatty acids associated with lower risk of diabetic retinopathy

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Researchers find herpes strain in the nervous system

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Nature Heals

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

 
Print Page
Email Article

Randomised, double-blind, placebo-controlled treatment trial of fluoxetine & graded exercise for CFS

  [ 89 votes ]   [ Discuss This Article ]
By Wearden AJ, Morriss RK, Mullis R, Strickland PL, Pearson DJ, Appleby L, Campbell IT, Morris JA • www.ProHealth.com • June 15, 1998


BACKGROUND: The Joint Working Group of the Royal Colleges of
Physicians, Psychiatrists and General Practitioners (1996)
recommended graded exercise and antidepressants for patients
with chronic fatigue syndrome. We assessed efficacy and
acceptability of these treatments.

METHOD: Six-month
prospective randomised placebo and therapist contact time
controlled trial with allocation to one of four treatment
cells: exercise and 20 mg fluoxetine, exercise and placebo
drug, appointments only and 20 mg fluoxetine, appointments and
placebo drug. Drug treatment was double blind and patients
were blind to assignment to exercise or appointments.

RESULTS:
Ninety-six (71%) of 136 patients completed the trial. Patients
were more likely to drop out of exercise than non-exercise
treatment (P = 0.05). In an intention to treat analysis,
exercise resulted in fewer patients with case level fatigue
than appointments only at 26 weeks (12 (18%) v. 4 (6%)
respectively P = 0.025) and improvement in functional work
capacity at 12 (P = 0.005) and 26 weeks (P = 0.03). Fluoxetine
had a significant effect on depression at week 12 only (P =
0.04). Exercise significantly improved health perception (P =
0.012) and fatigue (P = 0.028) at 28 weeks.

CONCLUSIONS:
Graded exercise produced improvements in functional work
capacity and fatigue, while fluoxetine improved depression
only.




Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map