ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Fighting Heartburn and Gerd Naturally – And Safely!

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Natural Bladder Control, Go Less and Live More

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Trimming the spare tire: Canola oil may cut belly fat

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

Curcumin Reverses the Cellular Damage of Chronic Stress

Probiotics improve cognition in Alzheimer's patients

The Onion: Cancer Fighter and Food Preserver

 
Print Page
Email Article

Markers of inflamm. & immune activation in chronic fatigue & Chronic Fatigue Syndrome (CFS)

  [ 22 votes ]   [ Discuss This Article ]
By Buchwald D, Wener MH, Pearlman T, Kith P • www.ProHealth.com • February 16, 1997


OBJECTIVE: Chronic fatigue syndrome (CFS) has been hypothesized to
result from immune activation. We examined the role of serum
markers of inflammation and immune activation among patients
with CFS and in those with chronic fatigue (CF) not meeting
the case definition.
METHODS: Assays for soluble interleukin
2 (IL-2) receptor, IL-6, C-reactive protein, beta
2-microglobulin, and neopterin were performed in 153 fatigued
patients in a referral clinic. Patients were classified
according to whether they met criteria for CFS, reported onset
of illness with a viral syndrome or had a temperature > 37.5
degrees C on examination.
RESULTS: Compared to control
subjects, mean concentrations of C-reactive protein, beta
2-microglobulin, and neopterin were higher in patients with
CFS (p < or = 0.01) and CF (p < or = 0.01). Results did not
distinguish CFS from CF. IL-6 was elevated among febrile
patients compared to those without this finding (p < or =
0.001), but other consistent differences between patient
subgroups were not observed. The presence of several markers
was highly correlated (p < 0.01).
CONCLUSION: Our findings
that levels of several markers were significantly correlated
points to a subset of patients with immune system activation.
Whether this phenomenon reflects an intercurrent, transient,
common condition, such as an upper respiratory infection, or
is the result of an ongoing illness associated process is
unknown. Overall, serum markers of inflammation and immune
activation are of limited diagnostic usefulness in the
evaluation of patients with CSF and CF.

MCM: Studied soluble IL-2 receptor, IL-6, C-reactive protein,
beta-2-microglobulin, and neopterin in 98 pts w CFS and 55 w
CF as well as controls. Found soluble IL-2 receptor and IL-6
levels were not significantly different. C-reactive protein,
beta-2-microglobulin, and neopterin levels were significantly
higher in both pt groups compared to controls.




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg FibroSleep™ Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

How Glutathione Can Save Your Life How Glutathione Can Save Your Life
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?
The New Dual Activation Pain Relief Cream The New Dual Activation Pain Relief Cream
Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map