ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Ultrasound Therapy for Fibromyalgia and Lyme Disease

Curcumin: The All In One Solution, Part 2

What Are the Benefits of Vitamin K2?

Vitamin D deficiency + high fat diet = metabolic syndrome

Why You Should Take Your Apple Cider Vinegar at Night

Use Burdock Oil to Promote Healthy Hair Growth

Meet Your Weight Loss Goals

People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, resea...

AMA journal associates iron deficiency with hearing loss

Why the Mediterranean Diet Is so Successful

 
Print Page
Email Article

An open study of the efficacy & adverse effects of moclobemide in patients with Chronic Fatigue Syndrome (CFS)

  [ 62 votes ]   [ Discuss This Article ]
By White PD, Cleary KJ • www.ProHealth.com • January 5, 1997


There is a strong association between the chronic fatigue
syndrome and both depressive illness and sleep disturbance,
but the efficacy of antidepressants is uncertain. We studied
the efficacy and adverse effects of moclobemide in patients
with chronic fatigue syndrome, stratifying the sample both by
co-morbid major depressive illness and by sleep disturbance.
Forty-nine patients with chronic fatigue syndrome were
recruited. Patients were given moclobemide up to 600 mg a day
for 6 weeks. Four (8%) patients dropped out, three because of
adverse effects. Adverse effects wee otherwise mild and
transient. On analysing the whole sample, there were
significant but small reductions in fatigue, depression,
anxiety and somatic amplification, as well as a modest overall
improvement. The greatest improvement occurred in those
individuals who had a co-morbid major depressive illness, with
seven out of 14 (50%) of such individuals rating themselves as
"much better" by 6 weeks, compared to six out of 31 (19%) of
those who were not depressed (31% difference, 95% CI 1-60%, P
= 0.04). Sleep disturbance had no effect on outcome.
Moclobemide may be indicated in patients with chronic fatigue
syndrome and a co-morbid major depressive disorder. A
randomized, placebo-controlled trial is needed to confirm
this. These results do not support moclobemide as an effective
treatment of chronic fatigue syndrome in the absence of a
major depressive disorder.




Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map