ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Meta-analysis adds evidence to association between omega-3 supplementation and lower heart rate

Friendly User's Guide for the Timing of Nutritional Supplements

The Health Benefits of Manuka Honey

Increase Your Magnesium Intake

Vitamin D supplementation could ease IBS symptoms

Top Tips to Boost Your Immunity

Essential Oils Lower Blood Pressure

11 Amazing Health Benefits of Using Baking Soda

Nicotinamide riboside shows promise for treatment of Alzheimer’s disease

Exercise, calcium, vitamin D, and other factors linked with fewer injurious falls

 
Print Page
Email Article

An open study of the efficacy & adverse effects of moclobemide in patients with Chronic Fatigue Syndrome (CFS)

  [ 62 votes ]   [ Discuss This Article ]
By White PD, Cleary KJ • www.ProHealth.com • January 5, 1997


There is a strong association between the chronic fatigue
syndrome and both depressive illness and sleep disturbance,
but the efficacy of antidepressants is uncertain. We studied
the efficacy and adverse effects of moclobemide in patients
with chronic fatigue syndrome, stratifying the sample both by
co-morbid major depressive illness and by sleep disturbance.
Forty-nine patients with chronic fatigue syndrome were
recruited. Patients were given moclobemide up to 600 mg a day
for 6 weeks. Four (8%) patients dropped out, three because of
adverse effects. Adverse effects wee otherwise mild and
transient. On analysing the whole sample, there were
significant but small reductions in fatigue, depression,
anxiety and somatic amplification, as well as a modest overall
improvement. The greatest improvement occurred in those
individuals who had a co-morbid major depressive illness, with
seven out of 14 (50%) of such individuals rating themselves as
"much better" by 6 weeks, compared to six out of 31 (19%) of
those who were not depressed (31% difference, 95% CI 1-60%, P
= 0.04). Sleep disturbance had no effect on outcome.
Moclobemide may be indicated in patients with chronic fatigue
syndrome and a co-morbid major depressive disorder. A
randomized, placebo-controlled trial is needed to confirm
this. These results do not support moclobemide as an effective
treatment of chronic fatigue syndrome in the absence of a
major depressive disorder.




Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get Energized with Malic Acid & Magnesium

Natural Remedies

Top 3 Nutrients to Detox the Liver and Soothe Digestion Top 3 Nutrients to Detox the Liver and Soothe Digestion
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map