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Possible relationship between chronic fatigue & postural tachycardia syndromes

  [ 22 votes ]   [ Discuss This Article ]
By De Lorenzo F, Hargreaves J, Kakkar VV • • October 6, 1996

Postural tachycardia syndrome refers to the development of symptoms
such as light-headedness, visual blurring, palpitations and
weakness on assuming an upright posture; these symptoms are
relieved by resuming a supine posture. This syndrome is
occasionally associated with idiopathic hypovolemia, impaired
vasomotor tone, deconditioning and autonomic neuropathy, but
has not been reported in association with chronic fatigue
syndrome (CFS). We describe five patients who satisfied the
CFS criteria of the Centres for Disease Control and
Prevention. Upright tilt-table testing induced significant
hypotension and increased heart rate in all five patients,
consistent with clinical and autonomic manifestation of
postural tachycardia syndrome.

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