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Depression in fatiguing illness: comparing patients with Chronic Fatigue Syndrome (CFS), multiple sclerosis & depression

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www.ProHealth.com • June 20, 1996


Because depression is commonly observed in the chronic fatigue
syndrome (CFS), the present study sought to determine whether
the symptom pattern is similar to that seen in clinically
depressed subjects (DEP). Individuals with multiple sclerosis
(MS) were chosen as an additional comparison group because MS
is a fatiguing illness of known organic etiology. The Beck
Depression Inventory (BDI) was used to compare categories of
depressive symptomatology. Absolute scores on the BDI were
higher for the depressed group on mood and self-reproach
symptoms, but were not higher than the CFS group on somatic
and vegetative items. Analysis of symptoms as a percentage of
total BDI score revealed no significant differences in mood
or vegetative items among the three groups. The CFS and MS
groups exhibited a significantly lower percentage of
self-reproach symptoms than DEP, whereas the DEP group showed
a lower percentage of somatic symptoms than the CFS and MS
groups.

Johnson SK, DeLuca J, Natelson BH




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