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Fibromyalgia (FM): chronobiological aspects

  [ 27 votes ]   [ Discuss This Article ] • December 3, 1994

The primary fibromyalgia syndrome (Weichteilrheumatismus)
shows a circadian rhythm of the symptoms [MCM: most prominent
in the early morning and in the early evening] and, moreover,
a seasonality of pain severeness. Although the
pathophysiologic mechanisms are unknown, the circadian
variations are well documented in the literature; the
seasonality of pain is sometimes clinically reported. In a
study on "healthy" workers, the seasonality of this disease is

Pollmann L

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